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Catalog Number:
01374
CAS Number:
2900-27-8
Boc-L-phenylglycine
Purity:
≥ 98.50% (HPLC)
Synonym(s):
Boc-L-Phg-OH, Boc-Phg-OH, (S-Boc-2-aminophenylacetic acid
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Product Information

Boc-L-phenylglycine is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Its unique structure allows for the introduction of phenyl groups, which can significantly influence the biological activity of peptides. Researchers often leverage Boc-L-phenylglycine in the development of bioactive compounds, particularly in the design of enzyme inhibitors and receptor ligands.

In addition to its role in peptide synthesis, Boc-L-phenylglycine serves as a chiral building block in asymmetric synthesis, providing a pathway to create enantiomerically pure compounds. Its versatility and effectiveness in modifying peptide sequences make it a preferred choice for chemists aiming to enhance the pharmacological properties of their products. With its proven track record in both academic and industrial settings, Boc-L-phenylglycine stands out as a crucial component for advancing drug discovery and development.

Synonyms
Boc-L-Phg-OH, Boc-Phg-OH, (S-Boc-2-aminophenylacetic acid
CAS Number
2900-27-8
Purity
≥ 98.50% (HPLC)
Molecular Formula
C13H17NO4
Molecular Weight
251.3
MDL Number
MFCD00065588
Melting Point
83-107 ?C
Appearance
White to off white powder
Optical Rotation
[a]D25 = +135.0 ± 4.5º (C=1% in MeOH)
Conditions
Store at RT
General Information
Synonyms
Boc-L-Phg-OH, Boc-Phg-OH, (S-Boc-2-aminophenylacetic acid
CAS Number
2900-27-8
Purity
≥ 98.50% (HPLC)
Molecular Formula
C13H17NO4
Molecular Weight
251.3
MDL Number
MFCD00065588
Melting Point
83-107 ?C
Appearance
White to off white powder
Optical Rotation
[a]D25 = +135.0 ± 4.5º (C=1% in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-phenylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals that target specific biological pathways.
  • Drug Development: Its unique structure enhances the solubility and stability of drug candidates, making it valuable in the formulation of new therapeutic agents.
  • Bioconjugation: Boc-L-phenylglycine is used in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents for targeted delivery in cancer therapies.
  • Research in Neuroscience: This compound is explored for its potential effects on neurotransmitter systems, contributing to studies aimed at understanding and treating neurological disorders.
  • Chiral Catalysis: It plays a role in asymmetric synthesis, where its chiral properties help in producing enantiomerically pure compounds, crucial for the pharmaceutical industry.

Citations