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Catalog Number:
01383
CAS Number:
78452-55-8
Boc-β-(2-thienyl)-D-alanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-Ala-3-(2-thienyl)-OH, (R-N-Boc-2-thienylalanine
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Product Information

Boc-b-(2-thienyl)-D-alanine is a versatile amino acid derivative that serves as a valuable building block in peptide synthesis and medicinal chemistry. This compound features a unique thienyl group, which enhances its potential for various applications in drug development and biochemical research. Its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions, making it an ideal candidate for the synthesis of complex peptides and biologically active molecules. Researchers have utilized Boc-b-(2-thienyl)-D-alanine in the development of novel therapeutics, particularly in the fields of oncology and neurobiology, where its structural properties can lead to improved bioactivity and selectivity.

The compound's distinct characteristics, such as its stability and compatibility with various coupling reactions, make it a preferred choice for professionals seeking to create innovative peptide-based drugs. Its ability to incorporate into diverse molecular frameworks opens avenues for the design of targeted therapies, enhancing the efficacy of treatments while minimizing side effects. With its growing relevance in pharmaceutical research, Boc-b-(2-thienyl)-D-alanine stands out as a key player in the advancement of peptide chemistry.

Synonyms
Boc-D-Ala-3-(2-thienyl)-OH, (R-N-Boc-2-thienylalanine
CAS Number
78452-55-8
Purity
≥ 99% (HPLC)
Molecular Formula
C12H17NO4S
Molecular Weight
271.3
MDL Number
MFCD00065591
PubChem ID
7017897
Melting Point
70-76 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -26 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-Ala-3-(2-thienyl)-OH, (R-N-Boc-2-thienylalanine
CAS Number
78452-55-8
Purity
≥ 99% (HPLC)
Molecular Formula
C12H17NO4S
Molecular Weight
271.3
MDL Number
MFCD00065591
PubChem ID
7017897
Melting Point
70-76 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -26 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-b-(2-thienyl)-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial in creating complex peptide structures used in pharmaceuticals.
  • Drug Development: Its unique thiophene structure can enhance the biological activity of drug candidates, making it valuable in the design of new therapeutics, particularly in oncology and neurology.
  • Bioconjugation: The compound can be used in bioconjugation processes to link drugs to targeting molecules, improving the specificity and efficacy of treatments, especially in targeted therapies.
  • Research in Neuroscience: It is employed in studies related to neurotransmitter systems, helping researchers understand the role of specific amino acids in neural signaling and potential implications for neurodegenerative diseases.
  • Material Science: The compound's properties make it suitable for developing novel materials with specific electronic or optical characteristics, which can be applied in sensors and organic electronics.

Citations