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Catalog Number:
01520
CAS Number:
53597-25-4
Protamine sulfate salt Salmon
Grade:
meets USP, EP specifications
Purity:
≥ 100 units of Heparin sodium/mg
Synonym(s):
Salmine from Salmon
Documents
$22.83 /1G
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Product Information

Protamine sulfate salt from salmon is a highly effective anticoagulant used primarily in clinical settings to reverse the effects of heparin during surgical procedures or in patients experiencing heparin overdose. This compound is a mixture of proteins derived from salmon sperm, known for its ability to bind to heparin, thereby neutralizing its anticoagulant properties. Its rapid action and safety profile make it an essential agent in cardiopulmonary bypass surgeries and other medical interventions where heparin is utilized.

In addition to its medical applications, protamine sulfate salt is also gaining attention in research settings, particularly in the development of drug delivery systems and gene therapy. Its unique properties allow for the encapsulation of nucleic acids, enhancing the stability and efficacy of therapeutic agents. Researchers appreciate its biocompatibility and ability to facilitate cellular uptake, making it a valuable tool in the advancement of innovative treatments. With its diverse applications and significant benefits, protamine sulfate salt from salmon stands out as a critical compound in both clinical and research environments.

Synonyms
Salmine from Salmon
CAS Number
53597-25-4
Purity
≥ 100 units of Heparin sodium/mg
Grade
meets USP, EP specifications
Molecular Weight
0.0
MDL Number
MFCD00132091
Appearance
White to almost white hygroscopic powder
Optical Rotation
[a]D20 = -65.0 to -85.0º (C=1 in 0.1 mol/L HCl)
Conditions
Store at 0-8 °C
General Information
Synonyms
Salmine from Salmon
CAS Number
53597-25-4
Purity
≥ 100 units of Heparin sodium/mg
Grade
meets USP, EP specifications
Molecular Weight
0.0
MDL Number
MFCD00132091
Appearance
White to almost white hygroscopic powder
Optical Rotation
[a]D20 = -65.0 to -85.0º (C=1 in 0.1 mol/L HCl)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Protamine sulfate salt Salmon is widely utilized in research focused on:

  • Anticoagulant Reversal: It is primarily used to reverse the effects of heparin, an anticoagulant, during surgical procedures or in patients experiencing excessive bleeding. This application is crucial in cardiac surgeries and other medical interventions where blood clotting needs to be carefully managed.
  • Pharmaceutical Formulations: The compound is employed in the formulation of injectable medications, particularly in the development of insulin products. Its ability to stabilize and prolong the action of insulin makes it valuable in diabetes management.
  • Research in Cardiovascular Medicine: Researchers use it to study the interactions between blood components and anticoagulants, helping to develop better treatments for heart diseases and improve patient outcomes.
  • Drug Delivery Systems: Protamine sulfate is explored in the development of nanoparticles for targeted drug delivery. Its properties allow for the encapsulation of various therapeutic agents, enhancing their efficacy and reducing side effects.
  • Gene Therapy Applications: It is also investigated for its role in gene therapy, where it can assist in delivering nucleic acids into cells, thus facilitating the treatment of genetic disorders.

Citations