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Catalog Number:
01545
5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-O-methylcytidine
Synonym(s):
DMT-NiBu-2'-O-methylcytidine
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-O-methylcytidine is a versatile nucleoside derivative that plays a crucial role in the field of molecular biology and biochemistry. This compound is particularly valued for its application in the synthesis of oligonucleotides, where it serves as a protective group for the nucleobase, enhancing the stability and efficiency of the synthesis process. Its unique structure allows for selective protection and deprotection, making it an essential tool for researchers involved in RNA and DNA manipulation.

In addition to its synthetic utility, this compound is also explored in therapeutic applications, particularly in the development of RNA-based drugs and gene therapies. The presence of the dimethoxytrityl group provides enhanced solubility and stability, which are critical for successful delivery and efficacy of nucleic acid therapeutics. Researchers and industry professionals can leverage the unique properties of 5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-O-methylcytidine to advance their work in genetic engineering, drug development, and molecular diagnostics.

Synonyms
DMT-NiBu-2'-O-methylcytidine
Molecular Formula
C35H39N3O7
Molecular Weight
613.72
MDL Number
MFCD00274124
Appearance
White to off white powder
Conditions
Store at 0-8°C
General Information
Synonyms
DMT-NiBu-2'-O-methylcytidine
Molecular Formula
C35H39N3O7
Molecular Weight
613.72
MDL Number
MFCD00274124
Appearance
White to off white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-O-methylcytidine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of modified RNA and DNA, enhancing the stability and functionality of oligonucleotides used in genetic research.
  • Drug Development: Its unique structure allows for the design of nucleoside analogs that can be used in antiviral and anticancer therapies, providing potential advantages over traditional compounds.
  • Biotechnology: Employed in the production of RNA-based therapeutics, this compound plays a crucial role in developing mRNA vaccines and gene therapies, which have gained prominence in recent years.
  • Diagnostic Tools: The compound is used in the development of sensitive assays for detecting specific nucleic acid sequences, aiding in disease diagnosis and monitoring.
  • Research Applications: It is utilized in various molecular biology techniques, such as PCR and sequencing, facilitating advancements in genomics and personalized medicine.

Citations