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Catalog Number:
01938
CAS Number:
5983-09-5
2',3'-Dideoxyuridine
Purity:
≥ 99% (HPLC)
Synonym(s):
ddU, 1-(2',3'-Dideoxy-β-ribofuranosyl)uracil
Documents
$86.23 /25MG
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Product Information

2',3'-Dideoxyuridine is a nucleoside analog that plays a crucial role in antiviral and anticancer research. This compound is particularly significant in the study of HIV and other viral infections, as it inhibits viral replication by interfering with the synthesis of viral DNA. Its unique structure allows it to mimic natural nucleosides, making it an effective tool in the development of antiviral therapies. Researchers have utilized 2',3'-Dideoxyuridine in various clinical studies, demonstrating its potential in combination therapies to enhance the efficacy of existing antiviral drugs.

In addition to its applications in virology, 2',3'-Dideoxyuridine is also explored in cancer research due to its ability to induce apoptosis in certain cancer cell lines. Its selective action on rapidly dividing cells makes it a candidate for further investigation in targeted cancer therapies. With its proven effectiveness and ongoing research, 2',3'-Dideoxyuridine continues to be a valuable compound for professionals in pharmaceutical and biomedical fields, offering promising avenues for therapeutic development.

Synonyms
ddU, 1-(2',3'-Dideoxy-β-ribofuranosyl)uracil
CAS Number
5983-09-5
Purity
≥ 99% (HPLC)
Molecular Formula
C9H12N2O4
Molecular Weight
212.21
MDL Number
MFCD00013359
PubChem ID
355836
Melting Point
127-129°C
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
ddU, 1-(2',3'-Dideoxy-β-ribofuranosyl)uracil
CAS Number
5983-09-5
Purity
≥ 99% (HPLC)
Molecular Formula
C9H12N2O4
Molecular Weight
212.21
MDL Number
MFCD00013359
PubChem ID
355836
Melting Point
127-129°C
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2',3'-Dideoxyuridine is widely utilized in research focused on

  • Antiviral Research: This compound is primarily used in the development of antiviral drugs, particularly for treating HIV and other viral infections. Its ability to inhibit viral replication makes it a valuable tool in pharmaceutical research.
  • Cancer Treatment: Researchers explore its potential in oncology, as it can interfere with DNA synthesis in cancer cells, offering a pathway for developing targeted cancer therapies.
  • Biochemical Studies: It serves as a crucial reagent in biochemical assays to study nucleic acid metabolism and the mechanisms of action of various enzymes, aiding in the understanding of cellular processes.
  • Gene Therapy: The compound is investigated for its role in gene therapy applications, where it can be used to modify genetic material, potentially correcting genetic disorders.
  • Comparative Studies: Its unique properties allow for comparative studies with other nucleoside analogs, helping researchers understand the differences in efficacy and safety profiles, which is essential for drug development.

Citations