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Catalog Number:
02103
CAS Number:
21090-30-2
3'-O-Acetylthymidine
Purity:
≥ 98% (HPLC)
Synonym(s):
3'-O-Acetyl-1-(2'-deoxy-β-D-ribofuranosyl)thymine
Documents
$65.40 /250MG
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Product Information

3'-O-Acetylthymidine is a versatile nucleoside derivative that plays a crucial role in molecular biology and pharmaceutical research. This compound is recognized for its ability to serve as a building block in the synthesis of nucleotides and nucleic acids, making it invaluable in the development of antiviral and anticancer therapies. Its unique acetyl group enhances its stability and solubility, facilitating its incorporation into various biochemical assays and applications. Researchers utilize 3'-O-Acetylthymidine in the synthesis of modified oligonucleotides, which can be employed in gene therapy, RNA interference, and other innovative genetic engineering techniques.

Additionally, this compound's structural characteristics allow for its use in drug formulation, where it can improve the pharmacokinetic properties of therapeutic agents. Its potential to act as a prodrug further expands its applicability in medicinal chemistry, offering enhanced bioavailability and targeted delivery. With its diverse applications in both research and industry, 3'-O-Acetylthymidine stands out as a key compound for professionals seeking to advance their work in molecular biology and drug development.

Synonyms
3'-O-Acetyl-1-(2'-deoxy-β-D-ribofuranosyl)thymine
CAS Number
21090-30-2
Purity
≥ 98% (HPLC)
Molecular Formula
C12H16N2O6
Molecular Weight
284.3
MDL Number
MFCD00056059
PubChem ID
279519
Appearance
White to off-white free flowing powder
Conditions
Store at ≤ -15 °C
General Information
Synonyms
3'-O-Acetyl-1-(2'-deoxy-β-D-ribofuranosyl)thymine
CAS Number
21090-30-2
Purity
≥ 98% (HPLC)
Molecular Formula
C12H16N2O6
Molecular Weight
284.3
MDL Number
MFCD00056059
PubChem ID
279519
Appearance
White to off-white free flowing powder
Conditions
Store at ≤ -15 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3'-O-Acetylthymidine is widely utilized in research focused on:

  • Nucleoside Synthesis: This compound serves as a key intermediate in the synthesis of various nucleosides, which are essential for DNA and RNA research. Its acetyl group enhances stability and solubility, making it easier to work with in laboratory settings.
  • Antiviral Research: It is explored for its potential antiviral properties, particularly against viruses that affect nucleic acid metabolism. Researchers are investigating its efficacy in developing new antiviral therapies.
  • Drug Development: The compound is being studied for its role in creating prodrugs, which can improve the bioavailability of therapeutic agents. This application is crucial in the pharmaceutical industry for enhancing drug effectiveness.
  • Biochemical Assays: It is used in various biochemical assays to study enzyme activity related to nucleic acid processes. This application helps researchers understand fundamental biological mechanisms.
  • Gene Therapy: 3'-O-Acetylthymidine is being researched for its potential use in gene therapy applications, where it may help deliver genetic material more effectively into cells, addressing challenges in current gene delivery methods.

Citations