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Catalog Number:
02111
CAS Number:
100898-62-2
5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-deoxycytidine
Purity:
≥ 99% (HPLC)
Synonym(s):
DMT-NiBu-dC
Documents
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-deoxycytidine is a specialized nucleoside derivative that plays a crucial role in the synthesis of oligonucleotides and nucleic acid research. This compound is particularly valued for its protective groups, which enhance the stability and efficiency of DNA synthesis processes. Its unique structure allows for improved incorporation into various nucleic acid sequences, making it an essential tool for researchers in molecular biology and genetic engineering.

In practical applications, this compound is widely used in the development of therapeutic oligonucleotides, including antisense therapies and RNA interference strategies. Its ability to facilitate the synthesis of modified nucleotides contributes to advancements in gene therapy and personalized medicine. Additionally, the presence of the dimethoxytrityl group provides excellent protection during synthesis, ensuring high yields and purity of the final products. Researchers and industry professionals can leverage this compound to enhance their nucleic acid-based projects, driving innovation in genetic research and therapeutic development.

Synonyms
DMT-NiBu-dC
CAS Number
100898-62-2
Purity
≥ 99% (HPLC)
Molecular Formula
C34H37N3O7
Molecular Weight
599.72
MDL Number
MFCD00058586
Conditions
Store at 0 - 8 °C
General Information
Synonyms
DMT-NiBu-dC
CAS Number
100898-62-2
Purity
≥ 99% (HPLC)
Molecular Formula
C34H37N3O7
Molecular Weight
599.72
MDL Number
MFCD00058586
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-deoxycytidine is widely utilized in research focused on:

  • Oligonucleotide Synthesis: This compound serves as a key building block in the synthesis of modified oligonucleotides, which are essential for various genetic research applications, including gene editing and RNA interference.
  • Antiviral Research: It is used in the development of antiviral agents, particularly those targeting viral RNA, offering potential therapeutic benefits in treating viral infections.
  • Drug Development: The compound plays a role in the formulation of nucleoside analogs, which can enhance the efficacy of existing antiviral drugs, providing researchers with new avenues for treatment.
  • Biotechnology: In biotechnological applications, it is employed in the production of DNA and RNA probes, which are vital for diagnostics and molecular biology studies.
  • Pharmaceutical Formulations: Its unique chemical properties allow for improved stability and bioavailability in drug formulations, making it a valuable asset in pharmaceutical research and development.

Citations