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Catalog Number:
02213
CAS Number:
5978-22-3
Nε-Z-L-lysine tert-butyl ester hydrochloride
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
L-Lys(Z)-OtBu·HCl
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Product Information

Ne-Z-L-lysine tert-butyl ester hydrochloride is a versatile compound widely utilized in the fields of biochemistry and pharmaceutical research. This derivative of lysine features a tert-butyl ester group, enhancing its solubility and stability, making it an ideal candidate for peptide synthesis and drug formulation. Its unique structure allows for the selective protection of amino groups, facilitating the development of complex biomolecules. Researchers often leverage this compound in the synthesis of peptide-based therapeutics, where its ability to improve bioavailability is particularly advantageous.

In addition to its applications in peptide synthesis, Ne-Z-L-lysine tert-butyl ester hydrochloride serves as a valuable intermediate in the production of various pharmaceuticals and agrochemicals. Its compatibility with a range of reaction conditions and its ease of handling make it a preferred choice among professionals seeking reliable and effective building blocks for their projects. The compound's favorable properties not only streamline the synthesis process but also enhance the overall efficiency of product development in both academic and industrial settings.

Synonyms
L-Lys(Z)-OtBu·HCl
CAS Number
5978-22-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H28N2O4·HCl
Molecular Weight
372.89
MDL Number
MFCD00038898
Melting Point
140 - 150 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 13.5 ± 1.5 º (C=2 in EtOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
L-Lys(Z)-OtBu·HCl
CAS Number
5978-22-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H28N2O4·HCl
Molecular Weight
372.89
MDL Number
MFCD00038898
Melting Point
140 - 150 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 13.5 ± 1.5 º (C=2 in EtOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ne-Z-L-lysine tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the pharmaceutical industry, where it helps create therapeutic proteins and hormones.
  • Drug Development: It plays a significant role in drug formulation, enhancing the solubility and stability of active pharmaceutical ingredients, which is crucial for effective drug delivery systems.
  • Bioconjugation: Researchers use it for bioconjugation processes, linking biomolecules such as antibodies to drugs, improving targeted therapy in cancer treatments.
  • Research in Biochemistry: It is employed in various biochemical studies to investigate protein interactions and enzyme activities, providing insights into metabolic pathways.
  • Cosmetic Formulations: The compound is also found in cosmetic products, where it acts as a stabilizer and enhances the texture and efficacy of formulations aimed at skin health.

Citations