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Catalog Number:
02327
CAS Number:
144-48-9
Iodoacetamide
Purity:
≥ 98.5%
Synonym(s):
2-Iodoacetamide, α-Iodoacetamide
Hazmat
Documents
$20.00 /5G
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Product Information

Iodoacetamide is a versatile chemical compound widely utilized in biochemical research and various industrial applications. Known for its ability to modify proteins, Iodoacetamide acts as a potent alkylating agent, making it invaluable in the study of protein structure and function. Researchers often employ it in proteomics to selectively label cysteine residues, facilitating the identification and quantification of proteins in complex mixtures. This property is particularly beneficial in the development of targeted therapies and in the exploration of disease mechanisms.

In addition to its applications in research, Iodoacetamide is also used in the synthesis of pharmaceuticals and agrochemicals, where its reactivity can be harnessed to create novel compounds with desired biological activities. Its unique ability to form stable adducts with thiol groups enhances its utility in various chemical reactions, setting it apart from similar compounds. Whether in academic laboratories or industrial settings, Iodoacetamide stands out as a crucial tool for advancing scientific knowledge and innovation.

Synonyms
2-Iodoacetamide, α-Iodoacetamide
CAS Number
144-48-9
Purity
≥ 98.5%
Molecular Formula
C2H4INO
Molecular Weight
185.0
MDL Number
MFCD00008028
PubChem ID
3727
Melting Point
91 - 95 °C
Appearance
White to light yellow to off-white crystal
Conditions
Store at 0 - 8 °C
General Information
Synonyms
2-Iodoacetamide, α-Iodoacetamide
CAS Number
144-48-9
Purity
≥ 98.5%
Molecular Formula
C2H4INO
Molecular Weight
185.0
MDL Number
MFCD00008028
PubChem ID
3727
Melting Point
91 - 95 °C
Appearance
White to light yellow to off-white crystal
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Iodoacetamide is widely utilized in research focused on:

  • Protein Modification: It serves as a potent alkylating agent, allowing researchers to modify proteins in order to study their structure and function, particularly in proteomics.
  • Biochemical Assays: Commonly used in assays to inhibit specific enzymes, aiding in the exploration of enzyme mechanisms and interactions.
  • Cell Biology: Employed in cell culture studies to investigate cellular responses and signaling pathways, particularly in cancer research.
  • Drug Development: Valuable in the pharmaceutical industry for developing new drugs by targeting cysteine residues in proteins, which can lead to the design of more effective therapeutics.
  • Analytical Chemistry: Utilized in mass spectrometry for labeling and quantifying biomolecules, enhancing the sensitivity and accuracy of analytical methods.

Citations