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Catalog Number:
02418
CAS Number:
132684-60-7
Fmoc-L-α-tert-butylglycine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-α-tert-butyl-Gly-OH, Fmoc-L-Tle-OH, (S-N-Fmoc-2-amino-3,3-dimethyl butanoic acid
Documents
$86.23 /1G
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Product Information

Fmoc-L-a-tert-butylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique tert-butyl side chain enhances solubility and stability, making it an ideal choice for researchers focused on developing complex peptide structures. The compound's ability to facilitate the formation of peptide bonds while maintaining the integrity of the amino acid sequence is particularly beneficial in the pharmaceutical industry, where precision and reliability are paramount.

In addition to its applications in peptide synthesis, Fmoc-L-a-tert-butylglycine is also employed in the development of biologically active compounds and as a building block in the synthesis of various pharmaceuticals. Its favorable properties, such as high purity and stability under standard laboratory conditions, make it a preferred choice among chemists and researchers. By incorporating this compound into your research or production processes, you can enhance the efficiency and effectiveness of your peptide synthesis, paving the way for innovative therapeutic solutions.

Synonyms
Fmoc-L-α-tert-butyl-Gly-OH, Fmoc-L-Tle-OH, (S-N-Fmoc-2-amino-3,3-dimethyl butanoic acid
CAS Number
132684-60-7
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.5
MDL Number
MFCD00065649
Appearance
White powder
Optical Rotation
[a]D20 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-α-tert-butyl-Gly-OH, Fmoc-L-Tle-OH, (S-N-Fmoc-2-amino-3,3-dimethyl butanoic acid
CAS Number
132684-60-7
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.5
MDL Number
MFCD00065649
Appearance
White powder
Optical Rotation
[a]D20 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-a-tert-butylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of specific functional groups that enhance the stability and solubility of the resulting peptides.
  • Drug Development: It is used in the pharmaceutical industry to create novel drug candidates, particularly in the development of peptide-based therapeutics that target various diseases.
  • Bioconjugation: The chemical is employed in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Protein Engineering: Researchers utilize this compound to modify amino acids in proteins, enabling the study of protein structure and function, which is essential for understanding biological processes.
  • Analytical Chemistry: It is also applied in analytical methods for characterizing biomolecules, providing insights into their behavior and interactions in various environments.

Citations