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Catalog Number:
02433
CAS Number:
86060-82-4
Nα-Fmoc-Nε-Z-L-lysine
Purity:
≥ 98% (HPLC, TLC)
Synonym(s):
Fmoc-L-Lys(Z)-OH
Documents
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Product Information

Na-Fmoc-Ne-Z-L-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which is crucial for the selective protection of the amino group during the synthesis of complex peptides. Its unique structure allows for enhanced stability and solubility, making it an ideal choice for researchers working in the fields of medicinal chemistry and biochemistry.

In practical applications, Na-Fmoc-Ne-Z-L-lysine is particularly valuable in the development of peptide-based therapeutics, where precise control over amino acid sequences is essential. Its use in solid-phase peptide synthesis (SPPS) facilitates the efficient assembly of peptides, enabling the production of high-purity compounds for further biological evaluation. Additionally, this compound can be employed in the design of peptide libraries for drug discovery, providing researchers with a powerful tool to explore novel therapeutic candidates. With its robust performance and reliability, Na-Fmoc-Ne-Z-L-lysine stands out as a preferred choice for professionals seeking to advance their research and development efforts.

Synonyms
Fmoc-L-Lys(Z)-OH
CAS Number
86060-82-4
Purity
≥ 98% (HPLC, TLC)
Molecular Formula
C29H30N2O6
Molecular Weight
502.6
MDL Number
MFCD00065662
Melting Point
100 - 130 °C
Appearance
White powder
Optical Rotation
[a]D20 = -10 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(Z)-OH
CAS Number
86060-82-4
Purity
≥ 98% (HPLC, TLC)
Molecular Formula
C29H30N2O6
Molecular Weight
502.6
MDL Number
MFCD00065662
Melting Point
100 - 130 °C
Appearance
White powder
Optical Rotation
[a]D20 = -10 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-Z-L-lysine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides. Its protective groups allow for selective reactions, making it easier to construct complex peptide sequences.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. The ability to modify lysine residues enhances the therapeutic potential and specificity of drug candidates.
  • Bioconjugation: This chemical is employed in bioconjugation processes, where it helps attach peptides to other molecules, such as antibodies or drugs, improving their delivery and efficacy in targeted therapies.
  • Research in Protein Engineering: It is valuable in protein engineering, allowing scientists to introduce specific functionalities into proteins, which can lead to advancements in biotechnology and synthetic biology.
  • Diagnostics: The compound can be utilized in the development of diagnostic tools, particularly in assays that require specific peptide interactions, enhancing the sensitivity and specificity of detection methods.

Citations