Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02469
CAS Number:
103213-31-6
Fmoc-3,5-diiodo-L-tyrosine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-3,5-diiodo-L-Tyr-OH
Documents
$74.81 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-3,5-diiodo-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protective group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block in the field of medicinal chemistry. Its unique structure, characterized by the presence of two iodine atoms on the aromatic ring, enhances its potential in various applications, including the development of radiolabeled compounds for imaging and therapeutic purposes.

Researchers and industry professionals benefit from Fmoc-3,5-diiodo-L-tyrosine's ability to facilitate the incorporation of iodine into peptides, which can be crucial for studying biological processes and developing targeted therapies. Its stability and compatibility with standard coupling reagents make it an ideal choice for solid-phase peptide synthesis. Additionally, the compound's unique properties may offer advantages over similar amino acid derivatives, particularly in applications requiring enhanced biological activity or specific targeting capabilities.

Synonyms
Fmoc-3,5-diiodo-L-Tyr-OH
CAS Number
103213-31-6
Purity
≥ 99% (HPLC)
Molecular Formula
C24H19I2NO5
Molecular Weight
655.23
MDL Number
MFCD00063330
Melting Point
210 - 225 °C
Appearance
White to off-white solid
Optical Rotation
[a]D22 = -13 ± 2 º (C=1.121 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-3,5-diiodo-L-Tyr-OH
CAS Number
103213-31-6
Purity
≥ 99% (HPLC)
Molecular Formula
C24H19I2NO5
Molecular Weight
655.23
MDL Number
MFCD00063330
Melting Point
210 - 225 °C
Appearance
White to off-white solid
Optical Rotation
[a]D22 = -13 ± 2 º (C=1.121 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,5-diiodo-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of iodine into peptide structures, which can enhance biological activity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing iodine-containing drugs, which can improve imaging and therapeutic applications in oncology.
  • Bioconjugation: The presence of the Fmoc protecting group allows for selective reactions in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Thyroid Hormones: Due to its structural similarity to tyrosine, it is used in studies related to thyroid hormones, helping researchers understand hormone synthesis and function.
  • Antibody Production: This compound can be utilized in the production of antibodies, particularly in the development of assays and diagnostics, enhancing the specificity and sensitivity of detection methods.

Citations