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Catalog Number:
02580
CAS Number:
135944-09-1
Fmoc-D-homophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-HomoPhe-OH, (R)-2-(Fmoc-amino)-4-phenyl-butyric acid
Documents
$37.56 /1G
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Product Information

Fmoc-D-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure allows for enhanced stability and solubility, making it an excellent choice for researchers looking to create complex peptides with high purity and yield. Fmoc-D-homophenylalanine is particularly valuable in the pharmaceutical industry for the development of peptide-based therapeutics, as it can facilitate the incorporation of non-natural amino acids into peptide sequences, thereby expanding the potential for novel drug candidates.

In addition to its applications in peptide synthesis, Fmoc-D-homophenylalanine has shown promise in various research fields, including materials science and biochemistry. Its ability to form stable interactions with other biomolecules makes it a useful tool for studying protein interactions and developing biomimetic materials. Researchers can leverage the unique properties of this compound to explore new avenues in drug design and delivery, ultimately contributing to advancements in therapeutic strategies.

Synonyms
Fmoc-D-HomoPhe-OH, (R)-2-(Fmoc-amino)-4-phenyl-butyric acid
CAS Number
135944-09-1
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.45
MDL Number
MFCD00151917
Melting Point
139 - 146 ºC
Appearance
White powder
Optical Rotation
[a]D20 = 8 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-HomoPhe-OH, (R)-2-(Fmoc-amino)-4-phenyl-butyric acid
CAS Number
135944-09-1
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.45
MDL Number
MFCD00151917
Melting Point
139 - 146 ºC
Appearance
White powder
Optical Rotation
[a]D20 = 8 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-homophenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex and diverse peptide sequences.
  • Drug Development: Its structural properties make it valuable in the pharmaceutical industry for developing peptide-based drugs, enhancing bioactivity and specificity in therapeutic applications.
  • Bioconjugation: Fmoc-D-homophenylalanine can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and targeted drug delivery systems.
  • Research in Neuroscience: This compound is instrumental in studying neuropeptides and their functions, contributing to advancements in understanding neurological disorders and potential treatments.
  • Protein Engineering: It plays a significant role in protein engineering, where modifications can enhance protein stability and functionality, benefiting various applications in biotechnology and synthetic biology.

Citations