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Catalog Number:
02715
CAS Number:
252049-12-0
Nα-Fmoc-Nε-nicotinoyl-D-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-Nε-nicotinoyl-D-lysine
Documents
$117.78 /1G
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Product Information

Na-Fmoc-Ne-nicotinoyl-D-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry. Its unique structure, incorporating a nicotinoyl moiety, enhances its potential for creating bioactive peptides that can target specific biological pathways, making it particularly relevant for pharmaceutical applications.

This compound is widely used in the development of peptide-based therapeutics, especially in the design of targeted drug delivery systems and in the synthesis of cyclic peptides, which often exhibit improved stability and bioactivity. Researchers appreciate Na-Fmoc-Ne-nicotinoyl-D-lysine for its ability to facilitate the incorporation of complex functionalities into peptides, thereby expanding the scope of peptide libraries for screening in drug discovery. Its favorable properties, including solubility and stability, further enhance its applicability in various research settings, making it a preferred choice for professionals seeking to innovate in peptide chemistry.

Synonyms
Fmoc-Nε-nicotinoyl-D-lysine
CAS Number
252049-12-0
Purity
≥ 98% (HPLC)
Molecular Formula
C27H27N3O5
Molecular Weight
473.5
MDL Number
MFCD00080277
PubChem ID
68761798
Melting Point
> 200 ºC
Optical Rotation
[a]D = +10.14 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-Nε-nicotinoyl-D-lysine
CAS Number
252049-12-0
Purity
≥ 98% (HPLC)
Molecular Formula
C27H27N3O5
Molecular Weight
473.5
MDL Number
MFCD00080277
PubChem ID
68761798
Melting Point
> 200 ºC
Optical Rotation
[a]D = +10.14 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-nicotinoyl-D-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it is used to create drug candidates that target specific receptors, enhancing the effectiveness of therapeutic agents. The nicotinoyl group can improve bioavailability and receptor affinity.
  • Bioconjugation: This chemical is valuable in linking biomolecules, such as proteins and nucleic acids, to therapeutic agents. This application is crucial in developing targeted therapies in cancer treatment.
  • Protein Engineering: Researchers utilize this compound to modify proteins for better stability and functionality. Its unique structure allows for the introduction of specific properties that can enhance protein performance.
  • Diagnostics: In the field of diagnostics, it plays a role in developing assays that detect specific biomolecules, contributing to advancements in personalized medicine and disease monitoring.

Citations