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Catalog Number:
02720
CAS Number:
55533-24-9
Boc-4-amino-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Phe(4-NH2)-OH, Boc-p-amino-L-Phe-OH, Boc-Phe(4-NH2)-OH
Documents
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Product Information

Boc-4-amino-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal building block for the development of bioactive peptides. Its unique structure allows for selective functionalization, enabling researchers to explore various modifications that can lead to novel therapeutic agents.

In the field of medicinal chemistry, Boc-4-amino-L-phenylalanine is particularly valuable for creating peptides with enhanced biological activity and specificity. It has been employed in the synthesis of peptide hormones, enzyme inhibitors, and other biologically relevant molecules. The compound's ability to facilitate the introduction of amino acid sequences that mimic natural proteins makes it a crucial tool for drug design and development. Researchers appreciate its compatibility with standard coupling reagents and its effectiveness in solid-phase peptide synthesis, ensuring high yields and purity in their projects.

Synonyms
Boc-L-Phe(4-NH2)-OH, Boc-p-amino-L-Phe-OH, Boc-Phe(4-NH2)-OH
CAS Number
55533-24-9
Purity
≥ 98% (HPLC)
Molecular Formula
C14H20N2O4
Molecular Weight
280.3
MDL Number
MFCD00038139
PubChem ID
571496
Appearance
White to off white powder
Optical Rotation
[a]D20 = +25 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Phe(4-NH2)-OH, Boc-p-amino-L-Phe-OH, Boc-Phe(4-NH2)-OH
CAS Number
55533-24-9
Purity
≥ 98% (HPLC)
Molecular Formula
C14H20N2O4
Molecular Weight
280.3
MDL Number
MFCD00038139
PubChem ID
571496
Appearance
White to off white powder
Optical Rotation
[a]D20 = +25 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-amino-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic proteins and biologically active peptides.
  • Drug Development: It is used in the pharmaceutical industry for the design of new drugs, especially those targeting neurological disorders, due to its structural similarity to amino acids involved in neurotransmitter function.
  • Bioconjugation: Researchers employ it in bioconjugation techniques to attach biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Research on Protein Folding: The compound aids in studies related to protein folding and stability, providing insights into diseases caused by misfolded proteins.
  • Custom Synthesis: It is utilized in custom synthesis projects for laboratories, allowing for tailored solutions in various research applications.

Citations