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Catalog Number:
02735
CAS Number:
51077-16-8
Boc-L-thiaproline
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Thz-OH, Boc-L-thiazolidine-4-carboxylic acid
Documents
$18.53 /1G
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Product Information

Boc-L-thiaproline is a valuable amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique thiazolidine ring structure, which enhances its stability and bioactivity compared to traditional amino acids. Its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions, making it an ideal choice for researchers looking to develop complex peptides with specific functionalities.

In the pharmaceutical industry, Boc-L-thiaproline has shown promise in the design of bioactive peptides and as a building block for drug candidates targeting various diseases. Its ability to mimic natural amino acids while providing distinct chemical properties opens avenues for innovative therapeutic applications. Researchers appreciate its versatility in synthetic pathways, as it can facilitate the incorporation of sulfur into peptide chains, which is crucial for the development of novel compounds with enhanced pharmacological profiles.

Synonyms
Boc-L-Thz-OH, Boc-L-thiazolidine-4-carboxylic acid
CAS Number
51077-16-8
Purity
≥ 99% (HPLC)
Molecular Formula
C9H15NO4S
Molecular Weight
233.3
MDL Number
MFCD00077002
PubChem ID
5147014
Melting Point
120 - 140 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -115 ± 5 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Thz-OH, Boc-L-thiazolidine-4-carboxylic acid
CAS Number
51077-16-8
Purity
≥ 99% (HPLC)
Molecular Formula
C9H15NO4S
Molecular Weight
233.3
MDL Number
MFCD00077002
PubChem ID
5147014
Melting Point
120 - 140 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -115 ± 5 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-thiaproline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of cyclic peptides that can enhance biological activity.
  • Drug Development: It plays a crucial role in medicinal chemistry, where it is used to design and synthesize novel drugs, especially those targeting specific receptors or enzymes.
  • Bioconjugation: Researchers leverage Boc-L-thiaproline for bioconjugation processes, allowing for the attachment of biomolecules to therapeutic agents, improving their efficacy and targeting capabilities.
  • Protein Engineering: Its unique structure aids in the modification of proteins, enabling scientists to create proteins with enhanced stability and functionality for various applications in biotechnology.
  • Research in Neuroscience: The compound is explored for its potential applications in neuroscience, particularly in studying the effects of modified peptides on neurological pathways and disorders.

Citations