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Catalog Number:
02871
CAS Number:
985-16-0
Nafcillin sodium salt
Synonym(s):
6-(2-Ethoxy-1-naphthamido)penicillin sodium salt, Sodium nafcillin
Antibiotic
Documents
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Product Information

Nafcillin is a semi-synthetic penicillin antibiotic that is primarily used in the treatment of infections caused by penicillinase-producing staphylococci. This compound is particularly effective against Gram-positive bacteria, making it a valuable asset in both clinical and research settings. Nafcillin's unique structure allows it to resist degradation by certain beta-lactamases, which enhances its efficacy in combating resistant bacterial strains. It is commonly utilized in the treatment of skin infections, pneumonia, and endocarditis, providing healthcare professionals with a reliable option for managing serious infections.

In addition to its therapeutic applications, Nafcillin is also utilized in microbiological research to study bacterial resistance mechanisms and antibiotic efficacy. Its ability to inhibit bacterial cell wall synthesis makes it a critical tool for researchers investigating new antimicrobial strategies. With its proven track record and specific action against resistant bacteria, Nafcillin stands out as a crucial compound in both clinical and laboratory environments, ensuring effective treatment options and advancing the understanding of antibiotic resistance.

Synonyms
6-(2-Ethoxy-1-naphthamido)penicillin sodium salt, Sodium nafcillin
CAS Number
985-16-0
Molecular Formula
C21H21N2O5SNa
Molecular Weight
436.5
MDL Number
MFCD00056863
PubChem ID
23675745
Appearance
White pale yellow powder
Conditions
Store at 0-8°C
Potency
≥ 850 µg/mg (Anhydrous basis)
General Information
Synonyms
6-(2-Ethoxy-1-naphthamido)penicillin sodium salt, Sodium nafcillin
CAS Number
985-16-0
Molecular Formula
C21H21N2O5SNa
Molecular Weight
436.5
MDL Number
MFCD00056863
PubChem ID
23675745
Appearance
White pale yellow powder
Conditions
Store at 0-8°C
Potency
≥ 850 µg/mg (Anhydrous basis)
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Nafcillin is widely utilized in research focused on:

  • Antibiotic Therapy: Primarily used to treat infections caused by penicillinase-producing staphylococci, making it essential in hospitals for managing resistant bacterial infections.
  • Pharmaceutical Development: Employed in the formulation of new antibiotic drugs, aiding researchers in developing more effective treatments against resistant strains.
  • Clinical Research: Used in studies assessing the efficacy of antibiotic treatments, providing valuable data on dosage and administration in clinical settings.
  • Veterinary Medicine: Applied in treating bacterial infections in animals, ensuring the health of livestock and pets, which is crucial for veterinary practices.
  • Microbiology Studies: Serves as a tool for microbiologists to study bacterial resistance mechanisms, helping to inform future antibiotic development strategies.

Citations