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Catalog Number:
03126
CAS Number:
161879-12-5
L-Phenylglycine tert-butyl ester hydrochloride
Purity:
≥ 99.5% (HPLC, Chiral purity)
Synonym(s):
L-Phg-OtBu·HCl, H-Phg-OtBu·HCl
Documents
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Product Information

L-Phenylglycine tert-butyl ester hydrochloride is a versatile compound widely utilized in the synthesis of pharmaceuticals and fine chemicals. This compound serves as a crucial intermediate in the production of various bioactive molecules, particularly in the development of amino acid derivatives and peptide synthesis. Its unique structure allows for enhanced solubility and stability, making it an ideal choice for researchers and industry professionals looking to streamline their synthesis processes.

In addition to its applications in medicinal chemistry, L-Phenylglycine tert-butyl ester hydrochloride is also employed in the field of organic synthesis, where it plays a significant role in the preparation of chiral building blocks. Its ability to facilitate asymmetric synthesis makes it a valuable asset for creating compounds with specific stereochemical configurations. Researchers appreciate its efficiency and effectiveness in producing high-purity products, which are essential for advancing drug development and other chemical applications.

Synonyms
L-Phg-OtBu·HCl, H-Phg-OtBu·HCl
CAS Number
161879-12-5
Purity
≥ 99.5% (HPLC, Chiral purity)
Molecular Formula
C12H17NO2·HCl
Molecular Weight
243.73
MDL Number
MFCD00153456
PubChem ID
12162440
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +84 ± 3.5º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-Phg-OtBu·HCl, H-Phg-OtBu·HCl
CAS Number
161879-12-5
Purity
≥ 99.5% (HPLC, Chiral purity)
Molecular Formula
C12H17NO2·HCl
Molecular Weight
243.73
MDL Number
MFCD00153456
PubChem ID
12162440
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +84 ± 3.5º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

L-Phenylglycine tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in the production of peptides, enhancing the efficiency of coupling reactions due to its stable structure, which is beneficial for researchers in medicinal chemistry.
  • Chiral Resolution: The compound plays a significant role in chiral resolution processes, allowing chemists to separate enantiomers effectively, which is crucial in the production of optically active substances.
  • Biochemical Research: It is utilized in studies related to enzyme activity and protein interactions, providing insights into biological mechanisms and aiding in the discovery of new therapeutic targets.
  • Material Science: This chemical is also explored in the development of new materials, particularly in creating polymers with specific properties, appealing to researchers in materials engineering.

Citations