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Catalog Number:
03710
CAS Number:
210820-99-8
Nα-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-His(Boc)-OH×CHA
Documents
$18.50 /1G
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Product Information

Na-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is crucial for the selective protection of the amino group during the synthesis of complex peptides. Its Boc (tert-butyloxycarbonyl) group further enhances its stability and compatibility in various coupling reactions, making it an ideal choice for researchers focusing on the development of biologically active peptides and drug candidates.

This compound is particularly beneficial in the synthesis of histidine-containing peptides, which are essential in various biological processes and have applications in drug formulation and delivery systems. Its unique structure allows for improved solubility and stability, facilitating easier handling and manipulation in laboratory settings. Researchers can leverage Na-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt to streamline their peptide synthesis workflows, ultimately leading to more efficient and effective research outcomes.

Synonyms
Fmoc-L-His(Boc)-OH×CHA
CAS Number
210820-99-8
Purity
≥ 97% (HPLC)
Molecular Formula
C26H27N3O6·6H13N
Molecular Weight
576.7
MDL Number
MFCD00153357
PubChem ID
4255658
Melting Point
137-149 °C
Appearance
White to cream colored powder
Optical Rotation
[a]D20 = -7 ±2º(C=2 in AcOH)
Conditions
Store at 0-8 °
General Information
Synonyms
Fmoc-L-His(Boc)-OH×CHA
CAS Number
210820-99-8
Purity
≥ 97% (HPLC)
Molecular Formula
C26H27N3O6·6H13N
Molecular Weight
576.7
MDL Number
MFCD00153357
PubChem ID
4255658
Melting Point
137-149 °C
Appearance
White to cream colored powder
Optical Rotation
[a]D20 = -7 ±2º(C=2 in AcOH)
Conditions
Store at 0-8 °
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and biologically active peptides.
  • Drug Development: It plays a significant role in pharmaceutical research, aiding in the development of new drugs by providing a stable histidine derivative that can enhance the efficacy of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Protein Engineering: Researchers utilize this chemical to modify proteins, enhancing their stability and activity, which is crucial for applications in biotechnology and enzyme engineering.
  • Diagnostics: Its properties make it valuable in diagnostic assays, where it can be used to create specific reagents that improve the sensitivity and specificity of tests for various diseases.

Citations