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Catalog Number:
03772
CAS Number:
608512-87-4
Fmoc-O-acetyl-D-serine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Ser(Ac)-OH
Documents
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Product Information

Fmoc-O-acetyl-D-serine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its acetylation enhances solubility and stability, making it an ideal choice for researchers focusing on the development of therapeutic peptides and biomolecules. Fmoc-O-acetyl-D-serine is particularly valuable in the fields of medicinal chemistry and biochemistry, where it serves as a building block for the synthesis of bioactive compounds, including enzyme inhibitors and peptide hormones.

In addition to its role in peptide synthesis, Fmoc-O-acetyl-D-serine can be employed in the design of novel drug candidates, offering researchers a reliable option for exploring structure-activity relationships. Its unique properties facilitate the development of compounds with improved pharmacological profiles, making it a preferred choice for professionals in pharmaceutical research. With its proven efficacy and versatility, Fmoc-O-acetyl-D-serine stands out as a key ingredient in the toolkit of modern chemists and biochemists.

Synonyms
Fmoc-D-Ser(Ac)-OH
CAS Number
608512-87-4
Purity
≥ 97% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.2
MDL Number
MFCD00077069
PubChem ID
75110780
Melting Point
159-165º C
Optical Rotation
=+23.0±1º (c=1.044 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Ser(Ac)-OH
CAS Number
608512-87-4
Purity
≥ 97% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.2
MDL Number
MFCD00077069
PubChem ID
75110780
Melting Point
159-165º C
Optical Rotation
=+23.0±1º (c=1.044 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-acetyl-D-serine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing new drugs, especially those targeting neurological disorders, due to its structural similarity to amino acids.
  • Bioconjugation: Researchers use it to create bioconjugates, which are essential in developing targeted therapies and diagnostics, enhancing the specificity of drug delivery systems.
  • Protein Engineering: The compound is valuable in protein engineering applications, enabling the modification of proteins to improve their stability and activity in various biotechnological processes.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for their potential effects on neurotransmitter systems, providing insights into brain function and disorders.

Citations