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Catalog Number:
03850
CAS Number:
85201-91-8
Z-O-tert-butyl-L-trans-4-hydroxyproline
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-L-Hyp(tBu)-OH
Documents
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Product Information

Z-O-tert-butyl-L-trans-4-hydroxyproline is a versatile compound widely utilized in the pharmaceutical and biochemical industries. This amino acid derivative is recognized for its unique structural properties, which enhance its stability and solubility, making it an ideal candidate for various applications. Researchers often leverage its ability to act as a chiral building block in the synthesis of bioactive molecules, particularly in the development of peptide-based drugs and other therapeutic agents. Its role in stabilizing protein structures and facilitating enzyme interactions underscores its significance in drug formulation and design.

In addition to its pharmaceutical applications, Z-O-tert-butyl-L-trans-4-hydroxyproline is also valuable in the field of materials science, where it can be employed in the synthesis of polymers and advanced materials. Its unique properties allow for the creation of materials with enhanced mechanical strength and thermal stability. The compound's compatibility with various solvents and its ease of incorporation into complex chemical systems make it a preferred choice for researchers and industry professionals seeking reliable and effective solutions in their projects.

Synonyms
Z-L-Hyp(tBu)-OH
CAS Number
85201-91-8
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO5
Molecular Weight
321.4
MDL Number
MFCD00153336
PubChem ID
2802356
Appearance
Light yellow oil
Optical Rotation
[a]D20 = -18.0 ± 2º (C=2 in DMF)
Conditions
Store at ≤ -18 °C
General Information
Synonyms
Z-L-Hyp(tBu)-OH
CAS Number
85201-91-8
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO5
Molecular Weight
321.4
MDL Number
MFCD00153336
PubChem ID
2802356
Appearance
Light yellow oil
Optical Rotation
[a]D20 = -18.0 ± 2º (C=2 in DMF)
Conditions
Store at ≤ -18 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-O-tert-butyl-L-trans-4-hydroxyproline is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is used in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders due to its ability to modulate neurotransmitter activity.
  • Peptide Synthesis: It serves as a building block in peptide synthesis, allowing researchers to create more stable and effective peptides for therapeutic applications, enhancing their bioavailability.
  • Protein Engineering: The compound is employed in protein engineering to introduce specific modifications that can improve protein stability and functionality, which is crucial in biotechnological applications.
  • Research on Collagen: It is used in studies related to collagen synthesis and stability, which is important for developing treatments for skin and joint disorders.
  • Cosmetic Formulations: The compound finds applications in cosmetic formulations aimed at improving skin hydration and elasticity, making it valuable in the beauty industry.

Citations