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Catalog Number:
03871
CAS Number:
71447-81-9
Z-L-α-aminobutyric acid N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-L-Abu-OSu
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Product Information

Z-L-a-aminobutyric acid N-hydroxysuccinimide ester is a versatile compound widely utilized in biochemical research and pharmaceutical applications. This ester is particularly valued for its role in peptide synthesis and drug development, where it serves as a coupling agent that enhances the efficiency of amide bond formation. Its unique structure allows for improved solubility and stability, making it an ideal choice for researchers looking to optimize their synthetic pathways. Additionally, the compound's ability to facilitate the conjugation of biomolecules opens up avenues for the development of targeted drug delivery systems and therapeutic agents.

In the realm of bioconjugation, Z-L-a-aminobutyric acid N-hydroxysuccinimide ester stands out due to its selective reactivity with amines, enabling the formation of stable linkages with proteins and other macromolecules. This property is particularly beneficial in the creation of antibody-drug conjugates, which are pivotal in cancer therapy. Researchers and industry professionals can leverage this compound to enhance the specificity and efficacy of their therapeutic formulations, ultimately leading to improved patient outcomes.

Synonyms
Z-L-Abu-OSu
CAS Number
71447-81-9
Purity
≥ 98% (HPLC)
Molecular Formula
C16H18N2O6
Molecular Weight
334.3
MDL Number
MFCD00191058
PubChem ID
12961228
Melting Point
63-72 °C
Optical Rotation
[a]D22 = -23 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-L-Abu-OSu
CAS Number
71447-81-9
Purity
≥ 98% (HPLC)
Molecular Formula
C16H18N2O6
Molecular Weight
334.3
MDL Number
MFCD00191058
PubChem ID
12961228
Melting Point
63-72 °C
Optical Rotation
[a]D22 = -23 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-a-aminobutyric acid N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a valuable reagent for attaching biomolecules, such as proteins or peptides, to surfaces or other molecules, enhancing the development of targeted drug delivery systems.
  • Peptide Synthesis: It plays a crucial role in the synthesis of peptides, allowing researchers to create complex structures with improved stability and bioactivity, which is essential in pharmaceutical development.
  • Diagnostics: The compound is used in the creation of diagnostic assays, facilitating the detection of specific biomolecules in various samples, thus aiding in disease diagnosis and monitoring.
  • Drug Development: Its application in formulating new drugs helps in improving the efficacy and safety profiles of therapeutic agents, making it a key player in pharmaceutical research.
  • Research in Neuroscience: This chemical is utilized in studies related to neurotransmitter systems, contributing to the understanding of neurological disorders and the development of potential treatments.

Citations