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Catalog Number:
03881
CAS Number:
52235-17-3
Z-D-leucine 4-nitrophenyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-D-Leu-ONp, (R)-Z-2-amino-4-methyl-pentanoic acid 4-nitrophenylester
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Product Information

Z-D-leucine 4-nitrophenyl ester is a valuable compound widely utilized in peptide synthesis and pharmaceutical research. This ester derivative of leucine features a 4-nitrophenyl group, enhancing its reactivity and making it an excellent choice for various applications in organic chemistry. Researchers often leverage its unique properties for the development of peptide-based drugs, where it serves as a key building block in the synthesis of biologically active peptides. Its ability to facilitate selective reactions allows for the creation of complex structures, which are essential in medicinal chemistry.

In addition to its role in drug development, Z-D-leucine 4-nitrophenyl ester is also employed in the study of enzyme kinetics and protein interactions. Its stability and compatibility with various reaction conditions make it a preferred choice for researchers aiming to explore the intricacies of peptide behavior in biological systems. By incorporating this compound into their workflows, scientists can enhance the efficiency and specificity of their synthetic processes, ultimately leading to more effective therapeutic agents.

Synonyms
Z-D-Leu-ONp, (R)-Z-2-amino-4-methyl-pentanoic acid 4-nitrophenylester
CAS Number
52235-17-3
Purity
≥ 99% (HPLC)
Molecular Formula
C20H22N2O6
Molecular Weight
386.4
MDL Number
MFCD00153338
PubChem ID
284201
Melting Point
90-97 °C
Optical Rotation
[α]D20 = +31 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-D-Leu-ONp, (R)-Z-2-amino-4-methyl-pentanoic acid 4-nitrophenylester
CAS Number
52235-17-3
Purity
≥ 99% (HPLC)
Molecular Formula
C20H22N2O6
Molecular Weight
386.4
MDL Number
MFCD00153338
PubChem ID
284201
Melting Point
90-97 °C
Optical Rotation
[α]D20 = +31 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-D-leucine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enabling researchers to create complex structures for various applications in biochemistry and pharmacology.
  • Drug Development: It plays a crucial role in the development of new pharmaceuticals, particularly in designing drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing scientists to attach biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Enzyme Inhibition: It is applied in studies aimed at understanding enzyme mechanisms, helping researchers identify potential inhibitors that could lead to new treatments for diseases.
  • Protein Engineering: This chemical is instrumental in protein engineering, where it aids in modifying proteins to improve their stability and functionality for industrial and therapeutic uses.

Citations