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Catalog Number:
03906
CAS Number:
200259-50-3
Nα-Fmoc-Nγ-4-methyltrityl-D-asparagine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Asn(Mtt)-OH
Documents
$86.23 /250MG
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Product Information

Na-Fmoc-Ng-4-methyltrityl-D-asparagine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique structure, characterized by the Ng-4-methyltrityl modification, enhances stability and solubility, making it an ideal choice for researchers focused on developing complex peptides and biologically active compounds.

In practical applications, Na-Fmoc-Ng-4-methyltrityl-D-asparagine is particularly valuable in the pharmaceutical industry for the synthesis of peptide-based therapeutics, including those targeting cancer and metabolic disorders. Its ability to improve the yield and purity of synthesized peptides sets it apart from similar compounds, providing researchers with a reliable tool for advancing their projects. With its robust performance in peptide synthesis, this compound is essential for professionals seeking to innovate in drug discovery and development.

Synonyms
Fmoc-D-Asn(Mtt)-OH
CAS Number
200259-50-3
Purity
≥ 98% (HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.72
MDL Number
MFCD00237161
PubChem ID
76401348
Appearance
White powder
Optical Rotation
[a]D25 = +14.2 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Asn(Mtt)-OH
CAS Number
200259-50-3
Purity
≥ 98% (HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.72
MDL Number
MFCD00237161
PubChem ID
76401348
Appearance
White powder
Optical Rotation
[a]D25 = +14.2 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-4-methyltrityl-D-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing researchers to construct complex peptides with high purity and yield.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in targeting specific biological pathways, which is essential for developing new medications.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules, enhancing the efficacy of diagnostics and therapeutics.
  • Research in Neuroscience: It is applied in studies investigating neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Protein Engineering: The compound assists in the modification of proteins, allowing scientists to create novel proteins with tailored functions for various industrial applications.

Citations