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Catalog Number:
03923
CAS Number:
82565-68-2
Fmoc-4-iodo-L-phenylalanine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Phe(4-I)-OH, Fmoc-p-iodo-L-Phe-OH, Fmoc-Phe(4-I)-OH
Documents
$29.34 /1G
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Product Information

Fmoc-4-iodo-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. The presence of the iodine atom on the phenyl ring enhances its utility in various applications, including medicinal chemistry and bioconjugation. Researchers appreciate its ability to facilitate the introduction of iodine into peptide structures, which can be crucial for radiolabeling and imaging studies.

In addition to its role in peptide synthesis, Fmoc-4-iodo-L-phenylalanine serves as a valuable building block in the development of novel therapeutics and biomolecules. Its unique properties allow for the creation of peptides with enhanced biological activity and specificity. This compound is particularly relevant in the fields of drug discovery and development, where the ability to modify peptide structures can lead to improved efficacy and reduced side effects. With its robust applications in both academic and industrial settings, Fmoc-4-iodo-L-phenylalanine is an essential tool for researchers aiming to innovate in peptide-based therapies.

Synonyms
Fmoc-L-Phe(4-I)-OH, Fmoc-p-iodo-L-Phe-OH, Fmoc-Phe(4-I)-OH
CAS Number
82565-68-2
Purity
≥ 97% (HPLC)
Molecular Formula
C24H20INO4
Molecular Weight
513.4
MDL Number
MFCD00672340
PubChem ID
4456487
Melting Point
200 - 220 °C (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = -14 to -16 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(4-I)-OH, Fmoc-p-iodo-L-Phe-OH, Fmoc-Phe(4-I)-OH
CAS Number
82565-68-2
Purity
≥ 97% (HPLC)
Molecular Formula
C24H20INO4
Molecular Weight
513.4
MDL Number
MFCD00672340
PubChem ID
4456487
Melting Point
200 - 220 °C (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = -14 to -16 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-iodo-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences and functionalities.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, particularly those targeting specific proteins or receptors.
  • Bioconjugation: The iodine atom in this compound facilitates bioconjugation, enabling the attachment of various biomolecules for applications in diagnostics and therapeutics.
  • Research in Cancer Therapeutics: The compound is being explored for its potential in cancer treatment, as it can be incorporated into peptides that selectively target cancer cells.
  • Fluorescent Labeling: Researchers use it for fluorescent labeling in studies involving protein interactions, enhancing the understanding of biological processes.

Citations