Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
03987
CAS Number:
2488-14-4
Na-Boc-L-histidine methyl ester
Purity:
≥ 99% (TLC)
Synonym(s):
Boc-L-His-OMe
Documents
$51.18 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Na-Boc-L-histidine methyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This derivative of histidine features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for various applications in organic synthesis. Researchers often leverage its unique properties to facilitate the formation of complex peptide structures, particularly in the development of biologically active compounds and drug candidates. Its imidazole side chain contributes to its role in enzyme catalysis and metal ion coordination, further expanding its utility in biochemical studies.

In addition to its applications in synthetic chemistry, Na-Boc-L-histidine methyl ester is also valuable in the field of medicinal chemistry, where it serves as a building block for the synthesis of histidine-containing peptides and proteins. The compound's favorable solubility and compatibility with various reaction conditions make it a preferred choice among researchers looking to explore the therapeutic potential of histidine derivatives. With its broad range of applications, Na-Boc-L-histidine methyl ester stands out as a crucial tool for advancing research in peptide chemistry and drug development.

Synonyms
Boc-L-His-OMe
CAS Number
2488-14-4
Purity
≥ 99% (TLC)
Molecular Formula
C12H19N3O4
Molecular Weight
269.3
MDL Number
MFCD00167635
PubChem ID
13048303
Melting Point
121-128 ºC
Appearance
White to off-white powder
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-His-OMe
CAS Number
2488-14-4
Purity
≥ 99% (TLC)
Molecular Formula
C12H19N3O4
Molecular Weight
269.3
MDL Number
MFCD00167635
PubChem ID
13048303
Melting Point
121-128 ºC
Appearance
White to off-white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-L-histidine methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require histidine residues, enhancing the efficiency of creating complex biomolecules.
  • Drug Development: It plays a significant role in the design of pharmaceuticals, especially in developing histidine-containing drugs, which can improve solubility and bioavailability.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies and diagnostics.
  • Protein Engineering: It aids in the modification of proteins to study their functions and interactions, providing insights that are vital for advancements in biotechnology and therapeutic applications.
  • Research on Enzyme Activity: This chemical is utilized in studies examining enzyme activity, particularly those involving histidine residues, helping to elucidate mechanisms of action and potential inhibitors.

Citations