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Catalog Number:
04059
CAS Number:
109183-71-3
Boc-L-2-cyclohexylglycine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Chg-OH, Boc-cyclohexyl-L-Gly-OH, (S-tert-Butoxycarbonylamino-cyclohexyl-acetic acid
Documents
$18.53 /1G
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Product Information

Boc-L-2-cyclohexylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a cyclohexyl side chain that enhances its lipophilicity, making it an excellent candidate for developing bioactive peptides with improved pharmacokinetic properties. Its Boc (tert-butyloxycarbonyl) protecting group allows for selective deprotection during synthesis, facilitating the incorporation of this amino acid into complex peptide structures. Researchers have found Boc-L-2-cyclohexylglycine particularly useful in the design of peptide-based therapeutics, where its unique structural characteristics can lead to enhanced stability and activity.

In addition to its applications in drug development, Boc-L-2-cyclohexylglycine serves as a valuable building block in the synthesis of various biologically active compounds. Its ability to mimic natural amino acids while providing distinct properties makes it a favored choice among chemists and biochemists. The compound's compatibility with standard coupling reagents and its favorable solubility profile further contribute to its utility in laboratory settings, making it an essential tool for researchers aiming to innovate in the fields of medicinal chemistry and peptide engineering.

Synonyms
Boc-L-Chg-OH, Boc-cyclohexyl-L-Gly-OH, (S-tert-Butoxycarbonylamino-cyclohexyl-acetic acid
CAS Number
109183-71-3
Purity
≥ 99% (HPLC)
Molecular Formula
C13H23NO4
Molecular Weight
257.3
MDL Number
MFCD00133638
PubChem ID
3559319
Melting Point
94 - 96 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 11 ± 2 º (C=1.1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Chg-OH, Boc-cyclohexyl-L-Gly-OH, (S-tert-Butoxycarbonylamino-cyclohexyl-acetic acid
CAS Number
109183-71-3
Purity
≥ 99% (HPLC)
Molecular Formula
C13H23NO4
Molecular Weight
257.3
MDL Number
MFCD00133638
PubChem ID
3559319
Melting Point
94 - 96 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 11 ± 2 º (C=1.1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-2-cyclohexylglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its unique structure enhances the stability and bioactivity of the resulting peptides.
  • Drug Development: Researchers leverage Boc-L-2-cyclohexylglycine in the design of new drug candidates, especially those targeting neurological disorders. Its ability to mimic natural amino acids makes it an attractive option for creating effective therapeutic agents.
  • Biotechnology: In biotechnological applications, this compound is used to modify proteins and enzymes, improving their functionality and stability. This is particularly beneficial in industrial processes where enzyme efficiency is crucial.
  • Research in Neuroscience: The compound is utilized in studies investigating receptor interactions and signaling pathways in the nervous system. Its properties allow for a better understanding of neuropharmacology and potential treatments for mental health conditions.
  • Analytical Chemistry: Boc-L-2-cyclohexylglycine is employed as a standard in analytical methods, helping researchers quantify amino acids and peptides in complex mixtures. This application is essential for quality control in pharmaceutical manufacturing.

Citations