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Catalog Number:
04085
CAS Number:
205526-38-1
Fmoc-p-phenyl-D-Phenylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-p-phenyl-D-Phenylalanine, Fmoc-D-Ala(4,4'-biphenyl)-OH
Documents
$60.00 /1G
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Product Information

Fmoc-p-phenyl-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis (SPPS). Its unique structure, characterized by the presence of two phenyl groups, enhances the stability and hydrophobicity of peptides, making it particularly valuable in the design of bioactive compounds and pharmaceuticals. Researchers appreciate its ability to facilitate the synthesis of complex peptides with improved solubility and bioavailability, which are crucial for therapeutic applications.

In addition to its role in peptide synthesis, Fmoc-p-phenyl-D-phenylalanine is also employed in the development of novel materials and drug delivery systems. Its properties allow for the fine-tuning of peptide sequences, enabling the creation of targeted therapies for various diseases, including cancer and neurodegenerative disorders. The compound's robust performance in both academic and industrial settings makes it an essential tool for chemists and biochemists aiming to innovate in the fields of medicinal chemistry and biotechnology.

Synonyms
Fmoc-p-phenyl-D-Phenylalanine, Fmoc-D-Ala(4,4'-biphenyl)-OH
CAS Number
205526-38-1
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C30H25NO4
Molecular Weight
463.52
MDL Number
MFCD00191199
PubChem ID
18450295
Melting Point
180 - 183 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 10 ±1 °(C=1 in DMF)
Conditions
Store at 0 - 8 °
General Information
Synonyms
Fmoc-p-phenyl-D-Phenylalanine, Fmoc-D-Ala(4,4'-biphenyl)-OH
CAS Number
205526-38-1
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C30H25NO4
Molecular Weight
463.52
MDL Number
MFCD00191199
PubChem ID
18450295
Melting Point
180 - 183 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 10 ±1 °(C=1 in DMF)
Conditions
Store at 0 - 8 °
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-p-phenyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing chemists to build complex peptides efficiently while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, particularly in oncology, where modified peptides can target cancer cells more effectively than traditional drugs.
  • Bioconjugation: Researchers use it to create bioconjugates, linking peptides to other biomolecules for applications in targeted drug delivery systems, enhancing therapeutic efficacy.
  • Material Science: The compound is used in developing advanced materials, such as hydrogels, which can be utilized in tissue engineering and regenerative medicine.
  • Analytical Chemistry: It aids in the development of analytical methods for detecting and quantifying peptides, improving the accuracy of research in protein studies.

Citations