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Catalog Number:
04134
CAS Number:
189937-46-0
Fmoc-3,3-diphenyl-D-alanine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-D-Ala(3,3-diphenyl)-OH, (R)-N-(Fmoc)-β-phenyl-phenylalanine
Documents
$88.83 /1G
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Product Information

Fmoc-3,3-diphenyl-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, characterized by the presence of two phenyl groups, enhances its stability and solubility, making it an ideal choice for researchers focused on synthesizing complex peptides with high purity and yield.

In the pharmaceutical industry, Fmoc-3,3-diphenyl-D-alanine plays a crucial role in the development of peptide-based therapeutics, particularly in the design of inhibitors and biologically active compounds. Its ability to facilitate the formation of diverse peptide sequences allows for the exploration of novel drug candidates. Researchers appreciate its compatibility with various coupling reagents and its efficiency in producing high-quality peptides, which are vital for advancing drug discovery and development processes.

Synonyms
Fmoc-D-Ala(3,3-diphenyl)-OH, (R)-N-(Fmoc)-β-phenyl-phenylalanine
CAS Number
189937-46-0
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C30H25NO4
Molecular Weight
463.5
MDL Number
MFCD00672338
PubChem ID
3629137
Appearance
White to off-white powder
Optical Rotation
[a]20D = 21 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Ala(3,3-diphenyl)-OH, (R)-N-(Fmoc)-β-phenyl-phenylalanine
CAS Number
189937-46-0
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C30H25NO4
Molecular Weight
463.5
MDL Number
MFCD00672338
PubChem ID
3629137
Appearance
White to off-white powder
Optical Rotation
[a]20D = 21 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,3-diphenyl-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure aids in the design of peptide-based drugs, particularly in enhancing the stability and bioavailability of therapeutic peptides.
  • Bioconjugation: Used in bioconjugation techniques, it helps in attaching biomolecules to surfaces or other molecules, which is crucial for developing biosensors and targeted drug delivery systems.
  • Research in Neuroscience: The compound is valuable in studying neuropeptides, contributing to the understanding of neurochemical pathways and potential treatments for neurological disorders.
  • Material Science: Its properties are leveraged in creating advanced materials, such as hydrogels, which can be used in drug delivery systems and tissue engineering applications.

Citations