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Catalog Number:
05132
CAS Number:
34702-60-8
Boc-pentafluoro-L-phenylalanine
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Boc-L-Phe(F)5-OH, Boc-pentafluoro-L-Phe-OH, (S-Boc-2-amino-3-(pentafluorophenyl)propionic acid
Documents
$51.18 /1G
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Product Information

Boc-pentafluoro-L-phenylalanine is a specialized amino acid derivative that features a unique pentafluorophenyl group, making it an invaluable tool in peptide synthesis and drug development. This compound is particularly beneficial for researchers focusing on the design of fluorinated peptides, which can enhance the pharmacokinetic properties of therapeutic agents. Its distinctive structure allows for improved binding affinities and stability in biological systems, making it a preferred choice in medicinal chemistry and biochemistry applications.

In addition, Boc-pentafluoro-L-phenylalanine serves as a versatile building block in the synthesis of complex molecules, enabling the incorporation of fluorine atoms that can significantly alter the physicochemical properties of the resulting compounds. This capability is especially advantageous in the development of novel pharmaceuticals and agrochemicals, where fluorine can enhance bioactivity and selectivity. Researchers and industry professionals will find this compound essential for advancing their projects in drug discovery and peptide engineering.

Synonyms
Boc-L-Phe(F)5-OH, Boc-pentafluoro-L-Phe-OH, (S-Boc-2-amino-3-(pentafluorophenyl)propionic acid
CAS Number
34702-60-8
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C14H14F5NO4
Molecular Weight
355.2
MDL Number
MFCD00151893
PubChem ID
2756814
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Phe(F)5-OH, Boc-pentafluoro-L-Phe-OH, (S-Boc-2-amino-3-(pentafluorophenyl)propionic acid
CAS Number
34702-60-8
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C14H14F5NO4
Molecular Weight
355.2
MDL Number
MFCD00151893
PubChem ID
2756814
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-pentafluoro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of fluorinated amino acids that enhance the stability and bioactivity of therapeutic peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry for designing novel drugs, especially those targeting specific receptors or enzymes, due to its unique fluorinated structure that can improve binding affinity.
  • Protein Engineering: Researchers use it to modify proteins, allowing for the exploration of structure-activity relationships, which can lead to the creation of more effective biopharmaceuticals.
  • Fluorine Chemistry: This compound is an essential tool in fluorine chemistry, aiding in the development of new materials and compounds with enhanced properties, such as increased hydrophobicity and thermal stability.
  • Analytical Chemistry: It is utilized in analytical methods to study protein interactions and stability, providing insights that are crucial for both academic research and industrial applications.

Citations