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Catalog Number:
05133
CAS Number:
136207-26-6
Boc-pentafluoro-D-phenylalanine
Purity:
≥ 98% (HPLC, Chiral HPLC)
Synonym(s):
Boc-D-Phe(F)5-OH, Boc-pentafluoro-D-Phe-OH, Boc-D-Phe(F)5-OH
Documents
$58.39 /1G
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Product Information

Boc-pentafluoro-D-phenylalanine is a specialized amino acid derivative that features a unique pentafluorophenyl group, making it an invaluable tool in peptide synthesis and medicinal chemistry. This compound is particularly advantageous for researchers focusing on the development of fluorinated pharmaceuticals, as the presence of fluorine can enhance the metabolic stability and bioavailability of drug candidates. Its Boc (tert-butyloxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptides with precision.

In practical applications, Boc-pentafluoro-D-phenylalanine is utilized in the design of peptide-based therapeutics, especially in the fields of oncology and neurology, where fluorinated compounds have shown promising results. The unique properties of this amino acid derivative enable chemists to explore new avenues in drug discovery, providing a competitive edge in the synthesis of innovative therapeutic agents. Its ability to improve the pharmacokinetic profiles of peptides makes it a sought-after choice for professionals aiming to enhance drug efficacy and safety.

Synonyms
Boc-D-Phe(F)5-OH, Boc-pentafluoro-D-Phe-OH, Boc-D-Phe(F)5-OH
CAS Number
136207-26-6
Purity
≥ 98% (HPLC, Chiral HPLC)
Molecular Formula
C14H14F5NO4
Molecular Weight
355.2
MDL Number
MFCD00151892
PubChem ID
2756814
Appearance
Pale white solid
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Phe(F)5-OH, Boc-pentafluoro-D-Phe-OH, Boc-D-Phe(F)5-OH
CAS Number
136207-26-6
Purity
≥ 98% (HPLC, Chiral HPLC)
Molecular Formula
C14H14F5NO4
Molecular Weight
355.2
MDL Number
MFCD00151892
PubChem ID
2756814
Appearance
Pale white solid
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-pentafluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals that require specific amino acid sequences.
  • Drug Development: Its unique fluorinated structure enhances the biological activity of drug candidates, making it useful in the design of more effective therapeutic agents.
  • Bioconjugation: The compound can be employed in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Material Science: Its properties make it suitable for developing advanced materials with specific functionalities, such as coatings that require high chemical resistance.
  • Research in Fluorinated Compounds: The incorporation of fluorine atoms in its structure allows for the exploration of new chemical properties and reactions, driving innovation in organic chemistry.

Citations