🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
05134
CAS Number:
198545-85-6
Fmoc-pentafluoro-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Phe(F)5-OH, Fmoc-pentafluoro-D-Phe-OH
Documents
$65.00 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-pentafluoro-D-phenylalanine is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique pentafluorophenyl group, which enhances its hydrophobicity and stability, making it an excellent choice for researchers focused on developing potent and selective peptide-based therapeutics. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing compatibility with various coupling reagents.

This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it is utilized in the synthesis of fluorinated peptides that can exhibit improved pharmacokinetic properties. Researchers have found that the incorporation of fluorinated amino acids can enhance the binding affinity of peptides to their targets, potentially leading to more effective drugs. With its unique properties and applications, Fmoc-pentafluoro-D-phenylalanine stands out as a vital tool for scientists aiming to innovate in peptide design and development.

Synonyms
Fmoc-D-Phe(F)5-OH, Fmoc-pentafluoro-D-Phe-OH
CAS Number
198545-85-6
Purity
≥ 98% (HPLC)
Molecular Formula
C24H16F5NO4
Molecular Weight
477.4
MDL Number
MFCD00672558
PubChem ID
2759203
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(F)5-OH, Fmoc-pentafluoro-D-Phe-OH
CAS Number
198545-85-6
Purity
≥ 98% (HPLC)
Molecular Formula
C24H16F5NO4
Molecular Weight
477.4
MDL Number
MFCD00672558
PubChem ID
2759203
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-pentafluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the stability and reactivity of the resulting peptides.
  • Drug Development: Its unique fluorinated structure can improve the pharmacokinetic properties of peptide-based drugs, making them more effective in targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation techniques, allowing researchers to attach fluorinated amino acids to proteins or other biomolecules, which can aid in imaging and therapeutic applications.
  • Material Science: In the development of advanced materials, this compound can be incorporated into polymers to enhance their thermal and chemical stability, making them suitable for various industrial applications.
  • Analytical Chemistry: It can be utilized as a standard in analytical methods, helping to improve the accuracy and reliability of measurements in complex mixtures.

Citations