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Catalog Number:
05140
CAS Number:
198545-89-0
Fmoc-D-thiaproline
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Thz-OH, Fmoc-D-thiazolidine-4-carboxylic acid
Documents
$79.22 /1G
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Product Information

Fmoc-D-thiaproline is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique thiazolidine ring structure, which enhances its stability and bioactivity compared to traditional amino acids. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains, making it an essential building block for researchers in the fields of medicinal chemistry and biochemistry.

The compound's distinct properties enable it to serve as a chiral auxiliary in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds. Additionally, Fmoc-D-thiaproline has shown promise in the development of novel therapeutics, particularly in targeting specific biological pathways. Its versatility and effectiveness in various applications make it a preferred choice for professionals seeking to innovate in peptide-based drug design and synthesis.

Synonyms
Fmoc-D-Thz-OH, Fmoc-D-thiazolidine-4-carboxylic acid
CAS Number
198545-89-0
Purity
≥ 99% (HPLC)
Molecular Formula
C19H17NO4S
Molecular Weight
355.4
MDL Number
MFCD00235911
PubChem ID
5195877
Melting Point
151-159 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +70 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Thz-OH, Fmoc-D-thiazolidine-4-carboxylic acid
CAS Number
198545-89-0
Purity
≥ 99% (HPLC)
Molecular Formula
C19H17NO4S
Molecular Weight
355.4
MDL Number
MFCD00235911
PubChem ID
5195877
Melting Point
151-159 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +70 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-thiaproline is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of cyclic peptides that can exhibit enhanced biological activity.
  • Drug Development: Researchers leverage Fmoc-D-thiaproline in the design of novel therapeutics, especially in the field of anti-cancer and anti-viral drugs, due to its unique structural properties that can improve drug efficacy.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, facilitating targeted drug delivery systems that enhance treatment precision.
  • Protein Engineering: The compound plays a critical role in the modification of proteins, allowing scientists to create proteins with altered properties for research in enzyme activity and stability.
  • Analytical Chemistry: Fmoc-D-thiaproline is utilized in analytical methods for characterizing complex mixtures, aiding in the identification of compounds in various samples.

Citations