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Catalog Number:
05206
CAS Number:
25616-33-5
Boc-Phe-Gly-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-phenylalanine glycine
Documents
$50.00 /1G
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Product Information

Boc-Phe-Gly-OH, also known as N-Boc-phenylglycine, is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers engaged in the development of complex peptides and biologically active molecules. Its unique structure allows for selective reactions, facilitating the synthesis of various peptide sequences that are crucial in drug development and therapeutic applications.

In addition to its role in peptide synthesis, Boc-Phe-Gly-OH is valuable in the production of peptide-based drugs and in the study of protein interactions. Its application extends to the fields of biochemistry and molecular biology, where it serves as a building block for creating modified peptides that can exhibit enhanced biological activity or specificity. Researchers appreciate its ease of use and the efficiency it brings to synthetic pathways, making it a preferred choice for those looking to innovate in peptide chemistry.

Synonyms
Boc-L-phenylalanine glycine
CAS Number
25616-33-5
Purity
≥ 99% (HPLC)
Molecular Formula
C16H22N2O5
Molecular Weight
322.36
MDL Number
MFCD00134859
PubChem ID
3112537
Melting Point
155 - 165 °C
Appearance
White powder
Optical Rotation
[a]D20 = -5 ± 0.5 º (C=1 in Dioxane) [a]D20 = -9.5 ± 0.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-phenylalanine glycine
CAS Number
25616-33-5
Purity
≥ 99% (HPLC)
Molecular Formula
C16H22N2O5
Molecular Weight
322.36
MDL Number
MFCD00134859
PubChem ID
3112537
Melting Point
155 - 165 °C
Appearance
White powder
Optical Rotation
[a]D20 = -5 ± 0.5 º (C=1 in Dioxane) [a]D20 = -9.5 ± 0.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-Phe-Gly-OH is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, which are essential in drug development and biochemistry. Its protective group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: In pharmaceutical research, Boc-Phe-Gly-OH is used to create peptide-based drugs. Its structure can be modified to improve the efficacy and stability of therapeutic agents, particularly in targeting specific biological pathways.
  • Bioconjugation: This chemical is employed in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents. This application is crucial in developing targeted therapies and diagnostic tools in oncology and other fields.
  • Research in Neuroscience: The compound is used in studies related to neuropeptides, which play a significant role in brain function and behavior. Researchers utilize it to explore the effects of peptides on neurological disorders.
  • Protein Engineering: Boc-Phe-Gly-OH facilitates the engineering of proteins with specific functionalities. This application is vital in biotechnology, where customized proteins are needed for various industrial processes, including enzyme production.

Citations