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Catalog Number:
06547
CAS Number:
17543-58-7
Z-4-fluoro-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-p-fluoro-L-Phe-OH, Z-L-Phe(4-F)-OH, (2S)-2-([(Benzyloxy)carbonyl]amino)-3-(4-fluorophenyl)propanoic acid
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Product Information

Z-4-fluoro-L-phenylalanine is a valuable amino acid derivative that has garnered attention in the fields of biochemistry and pharmaceutical research. This compound, characterized by its unique fluorinated phenyl group, serves as a crucial building block in the synthesis of peptide-based drugs and biologically active compounds. Its structural properties allow for enhanced interactions with biological targets, making it a promising candidate for the development of novel therapeutics, particularly in the treatment of various diseases, including cancer and neurological disorders.

Researchers appreciate Z-4-fluoro-L-phenylalanine for its ability to modify protein structures, thereby influencing their function and stability. This compound can be utilized in the design of enzyme inhibitors and as a tool for studying protein-ligand interactions. Its distinct features, such as improved solubility and bioavailability compared to non-fluorinated analogs, provide significant advantages in drug formulation and development. With its diverse applications in medicinal chemistry and biopharmaceuticals, Z-4-fluoro-L-phenylalanine stands out as a key player in advancing scientific research and therapeutic innovation.

Synonyms
Z-p-fluoro-L-Phe-OH, Z-L-Phe(4-F)-OH, (2S)-2-([(Benzyloxy)carbonyl]amino)-3-(4-fluorophenyl)propanoic acid
CAS Number
17543-58-7
Purity
≥ 98% (HPLC)
Molecular Formula
C17H16NO4F
Molecular Weight
317.31
MDL Number
MFCD00238489
PubChem ID
14036705
Melting Point
105 - 110 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -37 ± 1 º (C=1.075 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-p-fluoro-L-Phe-OH, Z-L-Phe(4-F)-OH, (2S)-2-([(Benzyloxy)carbonyl]amino)-3-(4-fluorophenyl)propanoic acid
CAS Number
17543-58-7
Purity
≥ 98% (HPLC)
Molecular Formula
C17H16NO4F
Molecular Weight
317.31
MDL Number
MFCD00238489
PubChem ID
14036705
Melting Point
105 - 110 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -37 ± 1 º (C=1.075 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-4-fluoro-L-phenylalanine is widely utilized in research focused on:

  • Drug Development: This compound serves as a valuable building block in the synthesis of novel pharmaceuticals, particularly in the development of targeted therapies for cancer treatment.
  • Biochemical Research: It is used in studies to investigate protein interactions and enzyme activities, helping researchers understand complex biological processes.
  • Peptide Synthesis: Z-4-fluoro-L-phenylalanine is incorporated into peptides to enhance their stability and bioactivity, making it essential in the field of medicinal chemistry.
  • Neuroscience: This compound is employed in studies related to neurotransmitter functions, contributing to the understanding of neurological disorders.
  • Analytical Chemistry: It is utilized as a standard in chromatographic techniques, aiding in the accurate analysis of amino acids in various samples.

Citations