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Catalog Number:
07054
CAS Number:
252049-08-4
Nα-Fmoc-Nγ-Z-L-2,4-diaminobutyric acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Dab(Z)-OH, (S)-4-Benzyloxycarbonylamino-2-(Fmoc-amino)butyric acid
Documents
$72.31 /1G
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Product Information

Na-Fmoc-Ng-Z-L-2,4-diaminobutyric acid is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability during synthesis and facilitates easy removal under mild conditions. Its unique structure allows for the introduction of diverse functionalities, making it an essential building block in the creation of complex peptides and biologically active molecules. Researchers and industry professionals appreciate its role in enhancing the solubility and bioavailability of peptide-based therapeutics, particularly in the fields of oncology and immunology.

The compound's ability to support the synthesis of peptides with specific sequences and modifications opens up new avenues for drug discovery and development. Its application extends to the production of peptide vaccines and targeted therapies, where precision and efficacy are paramount. With its favorable properties, Na-Fmoc-Ng-Z-L-2,4-diaminobutyric acid stands out as a reliable choice for chemists aiming to innovate in peptide chemistry and related fields.

Synonyms
Fmoc-L-Dab(Z)-OH, (S)-4-Benzyloxycarbonylamino-2-(Fmoc-amino)butyric acid
CAS Number
252049-08-4
Purity
≥ 99% (HPLC)
Molecular Formula
C27H26N2O6
Molecular Weight
474.51
MDL Number
MFCD02259487
PubChem ID
77896138
Melting Point
136 - 141 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Dab(Z)-OH, (S)-4-Benzyloxycarbonylamino-2-(Fmoc-amino)butyric acid
CAS Number
252049-08-4
Purity
≥ 99% (HPLC)
Molecular Formula
C27H26N2O6
Molecular Weight
474.51
MDL Number
MFCD02259487
PubChem ID
77896138
Melting Point
136 - 141 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-Z-L-2,4-diaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex biomolecules with high purity and yield.
  • Drug Development: It plays a crucial role in the development of new pharmaceuticals, especially in the design of peptide-based drugs that can target specific biological pathways more effectively than traditional small molecules.
  • Bioconjugation: The chemical is used in bioconjugation techniques, enabling researchers to attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to specific research needs, which allows researchers to obtain tailored solutions for their projects.

Citations