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Catalog Number:
07108
CAS Number:
257886-01-4
Fmoc-O-trityl-D-homoserine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-HomoSer(Trt)-OH
Documents
$90.00 /250MG
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Product Information

Fmoc-O-trityl-D-homoserine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for researchers in the field of organic chemistry and biochemistry. Its trityl group enhances stability and solubility, facilitating the formation of complex peptides and proteins.

In practical applications, Fmoc-O-trityl-D-homoserine is particularly valuable in the synthesis of therapeutic peptides, where precision and purity are paramount. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers aiming to develop novel pharmaceuticals or study protein interactions. The compound's ability to withstand various reaction conditions while maintaining its integrity sets it apart from similar amino acid derivatives, ensuring high yields and quality in peptide synthesis.

Synonyms
Fmoc-D-HomoSer(Trt)-OH
CAS Number
257886-01-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C38H33NO5
Molecular Weight
583.68
MDL Number
MFCD01631663
PubChem ID
13943581
Melting Point
68 - 73 °C
Appearance
Off-white crystals or crystalline powder
Optical Rotation
[a]D20 = 14 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-HomoSer(Trt)-OH
CAS Number
257886-01-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C38H33NO5
Molecular Weight
583.68
MDL Number
MFCD01631663
PubChem ID
13943581
Melting Point
68 - 73 °C
Appearance
Off-white crystals or crystalline powder
Optical Rotation
[a]D20 = 14 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-trityl-D-homoserine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting other functional groups.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, enhancing the stability and bioavailability of drug candidates.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Neuroscience: Its derivatives are employed in studies related to neuropeptides, aiding in the understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to the specific needs of researchers and industries requiring tailored solutions for their projects.

Citations