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Catalog Number:
07241
CAS Number:
170642-29-2
Fmoc-β-cyclopropyl-D-alanine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-β-cyclopropyl-D-Ala-OH, Fmoc-D-Ala(β-cyclopropyl)-OH
Documents
$95.00 /250MG
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Product Information

Fmoc-b-cyclopropyl-D-alanine is a valuable building block in peptide synthesis, particularly favored in the development of novel pharmaceuticals and bioconjugates. This compound features a cyclopropyl group, which enhances the structural diversity of peptides, making it an attractive choice for researchers aiming to create compounds with unique biological activities. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Its applications extend to drug discovery, where it can be utilized to design inhibitors or modulators of protein interactions, thus playing a crucial role in the development of targeted therapies.

Researchers and industry professionals will appreciate the compound's ability to facilitate the synthesis of complex peptides with improved pharmacokinetic properties. The cyclopropyl moiety can also influence the conformational flexibility and binding affinity of peptides, making Fmoc-b-cyclopropyl-D-alanine a strategic choice for those looking to enhance the efficacy of their peptide-based drugs. With its unique structural features and practical applications, this compound stands out as a key ingredient in modern medicinal chemistry.

Synonyms
Fmoc-β-cyclopropyl-D-Ala-OH, Fmoc-D-Ala(β-cyclopropyl)-OH
CAS Number
170642-29-2
Purity
≥ 97% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.3
MDL Number
MFCD02259484
PubChem ID
4712596
Appearance
White to pale white solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-β-cyclopropyl-D-Ala-OH, Fmoc-D-Ala(β-cyclopropyl)-OH
CAS Number
170642-29-2
Purity
≥ 97% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.3
MDL Number
MFCD02259484
PubChem ID
4712596
Appearance
White to pale white solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-b-cyclopropyl-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and diverse peptide sequences.
  • Drug Development: It plays a significant role in the design of peptide-based pharmaceuticals, particularly those targeting specific receptors, enhancing therapeutic efficacy and selectivity.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules, which is crucial for developing targeted drug delivery systems.
  • Research in Neuroscience: It is utilized in studying neuropeptides and their functions, providing insights into neurological pathways and potential treatments for neurodegenerative diseases.
  • Protein Engineering: The unique cyclopropyl group enhances the stability and folding of proteins, making it valuable in protein engineering applications aimed at improving enzyme activity or stability.

Citations