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Catalog Number:
07246
CAS Number:
136555-16-3
Fmoc-D-cyclopentylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Gly(cyclopentyl)-OH, (R-2-Cyclopentyl-2-(Fmoc-amino)-acetic acid
Documents
$148.22 /250MG
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Product Information

Fmoc-D-cyclopentylglycine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a cyclopentyl side chain, which enhances the structural diversity of peptides, making it an excellent choice for researchers aiming to create novel therapeutics. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. This unique combination of properties makes Fmoc-D-cyclopentylglycine particularly useful in the design of peptide-based drugs that require specific conformational characteristics to achieve desired biological activities.

In the pharmaceutical industry, Fmoc-D-cyclopentylglycine has been employed in the development of peptide inhibitors and agonists, showcasing its potential in targeting various biological pathways. Researchers appreciate its ability to improve the solubility and bioavailability of peptides, which is crucial for effective drug formulation. Additionally, its compatibility with standard coupling reagents and protocols streamlines the synthesis process, making it a preferred choice for both academic and industrial applications. Overall, Fmoc-D-cyclopentylglycine stands out as a versatile building block in peptide chemistry, offering significant advantages in the pursuit of innovative therapeutic solutions.

Synonyms
Fmoc-D-Gly(cyclopentyl)-OH, (R-2-Cyclopentyl-2-(Fmoc-amino)-acetic acid
CAS Number
136555-16-3
Purity
≥ 98% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.2
MDL Number
MFCD01311778
PubChem ID
66615358
Melting Point
184 - 190 °C
Appearance
Crystals or white powder
Optical Rotation
[a]20D = 10 ± 1 ° (C=1 in Methanol)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Gly(cyclopentyl)-OH, (R-2-Cyclopentyl-2-(Fmoc-amino)-acetic acid
CAS Number
136555-16-3
Purity
≥ 98% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.2
MDL Number
MFCD01311778
PubChem ID
66615358
Melting Point
184 - 190 °C
Appearance
Crystals or white powder
Optical Rotation
[a]20D = 10 ± 1 ° (C=1 in Methanol)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-cyclopentylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex structures with high purity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for designing novel drug candidates, especially those targeting specific receptors or pathways.
  • Bioconjugation: The Fmoc protecting group enables selective reactions in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other compounds, enhancing drug delivery systems.
  • Research in Neuroscience: Used in the development of peptide-based therapeutics, it aids in studying neurological pathways and potential treatments for neurodegenerative diseases.
  • Custom Peptide Libraries: The compound is essential for creating diverse peptide libraries, which are crucial for screening and identifying new bioactive compounds in various biological assays.

Citations