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Catalog Number:
07382
CAS Number:
14464-68-7
3-Trifluoromethyl-L-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
L-Phe(3-CF3)-OH, H-L-Phe(3-trifluoromethyl)-OH, H-Phe(3-CF3)-OH
Documents
$86.23 /250MG
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Product Information

3-Trifluoromethyl-L-phenylalanine is a unique amino acid derivative that has garnered attention in various fields, particularly in medicinal chemistry and pharmaceutical research. This compound features a trifluoromethyl group, which significantly enhances its biological activity and lipophilicity, making it a valuable building block for the synthesis of novel pharmaceuticals. Researchers utilize 3-Trifluoromethyl-L-phenylalanine in the development of targeted therapies, especially in the design of inhibitors that interact with specific biological targets. Its distinctive properties allow for modifications that can lead to improved efficacy and selectivity in drug development.

In addition to its applications in drug synthesis, this compound is also explored for its potential in agrochemical formulations and as a tool in biochemical research. The trifluoromethyl group can impart unique characteristics to the molecules, enhancing their stability and performance in various applications. With its promising features, 3-Trifluoromethyl-L-phenylalanine stands out as a versatile compound that can meet the needs of researchers and industry professionals seeking innovative solutions in their projects.

Synonyms
L-Phe(3-CF3)-OH, H-L-Phe(3-trifluoromethyl)-OH, H-Phe(3-CF3)-OH
CAS Number
14464-68-7
Purity
≥ 99% (HPLC)
Molecular Formula
C10H10F3NO2
Molecular Weight
233.19
MDL Number
MFCD00044945
PubChem ID
2777602
Melting Point
191-193 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = + 2 ± 1 ° (C=1, in 2N NaOH)
Conditions
Store at 0-8°C
General Information
Synonyms
L-Phe(3-CF3)-OH, H-L-Phe(3-trifluoromethyl)-OH, H-Phe(3-CF3)-OH
CAS Number
14464-68-7
Purity
≥ 99% (HPLC)
Molecular Formula
C10H10F3NO2
Molecular Weight
233.19
MDL Number
MFCD00044945
PubChem ID
2777602
Melting Point
191-193 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = + 2 ± 1 ° (C=1, in 2N NaOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Trifluoromethyl-L-phenylalanine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a building block in the synthesis of novel pharmaceuticals, particularly in the design of drugs targeting neurological disorders due to its unique electronic properties.
  • Peptide Synthesis: It is used in peptide synthesis to introduce trifluoromethyl groups, enhancing the stability and bioactivity of peptides, which is crucial in drug formulation.
  • Biochemical Research: Researchers leverage its properties to study protein interactions and enzyme activities, providing insights into metabolic pathways and disease mechanisms.
  • Material Science: The compound is explored in creating advanced materials with specific thermal and electrical properties, beneficial in electronics and nanotechnology.
  • Fluorinated Compounds Research: It plays a significant role in the development of fluorinated compounds, which are known for their unique characteristics in pharmaceuticals and agrochemicals, offering advantages over non-fluorinated analogs.

Citations