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Catalog Number:
07391
CAS Number:
82317-83-7
Boc-p-trifluoromethyl-D-phenylalanine
Purity:
≥ 99.5% (Chiral HPLC, HPLC)
Synonym(s):
Boc-D-Phe(4-CF3)-OH, Boc-D-Phe(4-trifluoromethyl)-OH
Documents
$134.70 /1G
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Product Information

Boc-p-trifluoromethyl-D-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a trifluoromethyl group, which enhances its lipophilicity and metabolic stability, making it an ideal candidate for the development of novel therapeutics. Its unique structure allows researchers to explore its applications in drug design, particularly in creating selective inhibitors and modulators for various biological targets.

In addition to its role in pharmaceutical research, Boc-p-trifluoromethyl-D-phenylalanine is also employed in the synthesis of complex peptides, providing a versatile building block for chemists. Its protective Boc (tert-butyloxycarbonyl) group facilitates easy handling and purification during synthesis, ensuring high yields and purity. This compound's distinctive properties and practical applications make it an essential tool for researchers and industry professionals aiming to innovate in the fields of biochemistry and drug discovery.

Synonyms
Boc-D-Phe(4-CF3)-OH, Boc-D-Phe(4-trifluoromethyl)-OH
CAS Number
82317-83-7
Purity
≥ 99.5% (Chiral HPLC, HPLC)
Molecular Formula
C15H18F3NO4
Molecular Weight
333.31
MDL Number
MFCD00797557
PubChem ID
2756832
Melting Point
131 - 133 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 22 ± 1 º ( C=1 in DMF )
Conditions
Store at 0 - 8°C
General Information
Synonyms
Boc-D-Phe(4-CF3)-OH, Boc-D-Phe(4-trifluoromethyl)-OH
CAS Number
82317-83-7
Purity
≥ 99.5% (Chiral HPLC, HPLC)
Molecular Formula
C15H18F3NO4
Molecular Weight
333.31
MDL Number
MFCD00797557
PubChem ID
2756832
Melting Point
131 - 133 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 22 ± 1 º ( C=1 in DMF )
Conditions
Store at 0 - 8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-p-trifluoromethyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals that target specific biological pathways.
  • Drug Development: Its unique trifluoromethyl group enhances the lipophilicity and metabolic stability of drug candidates, making it valuable in the design of new therapeutic agents.
  • Biochemical Research: Researchers use this compound to study protein interactions and enzyme activity, providing insights into various biochemical processes.
  • Material Science: The compound finds applications in creating advanced materials with specific properties, such as improved thermal stability and chemical resistance.
  • Fluorinated Compounds Research: Its incorporation into studies of fluorinated compounds helps in understanding their behavior and potential applications in medicinal chemistry.

Citations