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Catalog Number:
11629
CAS Number:
152436-04-9
Fmoc-α-methyl-D-phenylalanine
Purity:
≥ 99.5% (HPLC)
Synonym(s):
Fmoc-α-Me-D-Phe-OH, Fmoc-(R)-2-amino-2-methyl-3-phenylpropanoic acid
Documents
$154.93 /1G
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Product Information

Fmoc-a-methyl-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure enhances stability and solubility, making it an ideal choice for researchers aiming to create complex peptides with high purity and yield.

In the pharmaceutical industry, Fmoc-a-methyl-D-phenylalanine serves as a building block for the synthesis of bioactive peptides and can be employed in the development of novel therapeutics. Its application extends to the creation of peptide-based drugs, where its ability to mimic natural amino acids can lead to improved pharmacological properties. Researchers appreciate its compatibility with various coupling reagents, facilitating efficient synthesis processes. With its robust profile, this compound stands out as a key ingredient for advancing peptide chemistry and drug discovery.

Synonyms
Fmoc-α-Me-D-Phe-OH, Fmoc-(R)-2-amino-2-methyl-3-phenylpropanoic acid
CAS Number
152436-04-9
Purity
≥ 99.5% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD02259493
PubChem ID
17750303
Appearance
White powder
Optical Rotation
[a]D25 = 24 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-α-Me-D-Phe-OH, Fmoc-(R)-2-amino-2-methyl-3-phenylpropanoic acid
CAS Number
152436-04-9
Purity
≥ 99.5% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD02259493
PubChem ID
17750303
Appearance
White powder
Optical Rotation
[a]D25 = 24 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-a-methyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors or pathways.
  • Bioconjugation: Researchers use it to facilitate bioconjugation processes, linking peptides to other molecules like antibodies or drugs, enhancing therapeutic efficacy.
  • Research in Neuroscience: This compound is employed in studies related to neuropeptides, helping scientists understand neurological functions and potential treatments for disorders.
  • Protein Engineering: It is utilized in protein engineering applications, allowing for the modification of proteins to improve their stability and functionality in various biotechnological processes.

Citations