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Catalog Number:
11811
CAS Number:
144222-22-0
1-Boc-4-(aminomethyl)piperidine
Purity:
≥ 98% (Assay)
Synonym(s):
Boc-4-(aminomethyl)piperidine, Piperidin-4-ylmethyl-carbamic acid tert-butyl ester
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Product Information

Boc-4-(aminomethyl)piperidine is a versatile chemical compound widely utilized in the field of organic synthesis and medicinal chemistry. This compound features a tert-butyl carbamate protecting group, which enhances its stability and reactivity, making it an ideal intermediate in the synthesis of various pharmaceuticals and bioactive molecules. Its unique structure allows for the introduction of amine functionalities, which are crucial in the development of new therapeutic agents. Researchers often leverage Boc-4-(aminomethyl)piperidine in the preparation of piperidine derivatives, which are known for their diverse biological activities, including anti-inflammatory and analgesic properties.

In addition to its role in drug discovery, Boc-4-(aminomethyl)piperidine serves as a valuable building block in the synthesis of complex organic compounds. Its ability to undergo various chemical transformations, such as acylation and alkylation, makes it a preferred choice for chemists looking to streamline their synthetic pathways. This compound's favorable properties and practical applications position it as a key player in the pharmaceutical and chemical industries, offering significant advantages over similar compounds in terms of reactivity and ease of handling.

Synonyms
Boc-4-(aminomethyl)piperidine, Piperidin-4-ylmethyl-carbamic acid tert-butyl ester
CAS Number
144222-22-0
Purity
≥ 98% (Assay)
Molecular Formula
C11H22N2O2
Molecular Weight
214.28
MDL Number
MFCD01631214
PubChem ID
736817
Density
1.013 g/mL at 25 °C
Appearance
Colorless to light yellow liquid
Boiling Point
237 - 238 °C
Refractive Index
n20/D 1.473
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-4-(aminomethyl)piperidine, Piperidin-4-ylmethyl-carbamic acid tert-butyl ester
CAS Number
144222-22-0
Purity
≥ 98% (Assay)
Molecular Formula
C11H22N2O2
Molecular Weight
214.28
MDL Number
MFCD01631214
PubChem ID
736817
Density
1.013 g/mL at 25 °C
Appearance
Colorless to light yellow liquid
Boiling Point
237 - 238 °C
Refractive Index
n20/D 1.473
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-(aminomethyl)piperidine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a versatile building block in the synthesis of various pharmaceutical agents, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, enhancing the stability and solubility of peptides, which is crucial for drug formulation.
  • Bioconjugation: The compound can be employed in bioconjugation processes, allowing for the attachment of biomolecules to drugs, improving their efficacy and targeting capabilities.
  • Research in Neuroscience: Its derivatives are studied for their potential effects on neurotransmitter systems, providing insights into treatments for conditions like depression and anxiety.
  • Material Science: It finds applications in creating functional materials, such as polymers with specific properties, useful in various industrial applications.

Citations