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Catalog Number:
12067
CAS Number:
213271-05-7, 1272755-15-3
trans-L-4-Hydroxyproline 4-nitroanilide hydrochloride
Purity:
≥ 99% (Assay by titration, HPLC)
Synonym(s):
L-Hyp-pNA·HCl, (2S,4R-4-Hydroxypyrrolidine-2-carboxylic acidp-nitroanilide hydrochloride, H-Hyp-pNA·HCl
Documents
$68.40 /250MG
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Product Information

trans-L-4-Hydroxyproline 4-nitroanilide hydrochloride is a specialized compound that plays a significant role in biochemical research and pharmaceutical applications. This compound is recognized for its unique structural properties, which make it a valuable tool in the study of protein synthesis and enzyme activity. Its ability to act as a substrate or inhibitor in various enzymatic reactions allows researchers to explore metabolic pathways and develop new therapeutic strategies.

In the pharmaceutical industry, trans-L-4-Hydroxyproline 4-nitroanilide hydrochloride is particularly useful in the development of drugs targeting collagen-related disorders, as it can mimic natural amino acids involved in collagen synthesis. This compound's stability and solubility enhance its applicability in both in vitro and in vivo studies, making it an essential reagent for researchers focused on drug discovery and development. Its unique properties also provide advantages over similar compounds, offering improved specificity and efficacy in experimental applications.

Synonyms
L-Hyp-pNA·HCl, (2S,4R-4-Hydroxypyrrolidine-2-carboxylic acidp-nitroanilide hydrochloride, H-Hyp-pNA·HCl
CAS Number
213271-05-7, 1272755-15-3
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C11H13N3O4·HCl
Molecular Weight
287.74
MDL Number
MFCD00190930
PubChem ID
132935969
Melting Point
247 - 258 °C
Appearance
Off-white or white crystalline powder
Optical Rotation
[a]20D = -12 ± 1 º (C=0.5 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
L-Hyp-pNA·HCl, (2S,4R-4-Hydroxypyrrolidine-2-carboxylic acidp-nitroanilide hydrochloride, H-Hyp-pNA·HCl
CAS Number
213271-05-7, 1272755-15-3
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C11H13N3O4·HCl
Molecular Weight
287.74
MDL Number
MFCD00190930
PubChem ID
132935969
Melting Point
247 - 258 °C
Appearance
Off-white or white crystalline powder
Optical Rotation
[a]20D = -12 ± 1 º (C=0.5 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

trans-L-4-Hydroxyproline 4-nitroanilide hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound is essential in the synthesis of peptides, particularly for creating modified peptides that can enhance stability and bioactivity.
  • Drug Development: It plays a significant role in pharmaceutical research, especially in the development of new drugs targeting specific biological pathways, thanks to its unique structural properties.
  • Biochemical Assays: Researchers use it in various biochemical assays to study enzyme activity and protein interactions, providing valuable insights into metabolic processes.
  • Material Science: The compound is also explored in the development of new materials, particularly those that require specific chemical functionalities for enhanced performance.
  • Cosmetic Formulations: Its properties make it a candidate for use in cosmetic products, where it can contribute to skin hydration and overall product efficacy.

Citations