Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
12376
CAS Number:
212651-51-9
Fmoc-3,5-diiodo-D-tyrosine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-3,5-diiodo-D-Tyr-OH
Documents
$67.60 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-3,5-diiodo-D-tyrosine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is recognized for its unique properties, including the presence of iodine atoms, which enhance its biological activity and stability. Researchers and industry professionals utilize Fmoc-3,5-diiodo-D-tyrosine in the synthesis of iodinated peptides, which are essential in various applications such as radiolabeling and targeted therapies. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains, making it a valuable tool in solid-phase peptide synthesis.

The compound's ability to introduce iodine into peptide sequences can significantly improve the pharmacological properties of the resulting peptides, making them more effective in therapeutic applications. Fmoc-3,5-diiodo-D-tyrosine is particularly beneficial in the development of radiopharmaceuticals for diagnostic imaging and in the study of receptor interactions. Its versatility and effectiveness in enhancing peptide functionality make it an indispensable asset for researchers focused on innovative drug design and development.

Synonyms
Fmoc-3,5-diiodo-D-Tyr-OH
CAS Number
212651-51-9
Purity
≥ 97% (HPLC)
Molecular Formula
C24H19I2NO5
Molecular Weight
655.23
MDL Number
MFCD00270484
PubChem ID
4140855
Melting Point
202-208 °C
Appearance
Off-white powder
Optical Rotation
[a]D20 = +14 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-3,5-diiodo-D-Tyr-OH
CAS Number
212651-51-9
Purity
≥ 97% (HPLC)
Molecular Formula
C24H19I2NO5
Molecular Weight
655.23
MDL Number
MFCD00270484
PubChem ID
4140855
Melting Point
202-208 °C
Appearance
Off-white powder
Optical Rotation
[a]D20 = +14 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,5-diiodo-D-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of iodine into peptide structures, which can enhance their biological activity.
  • Drug Development: Its unique properties make it valuable in the development of novel pharmaceuticals, especially those targeting thyroid-related conditions or cancer therapies, where iodine plays a critical role in the mechanism of action.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, which can improve targeting and efficacy in therapeutic applications.
  • Research in Molecular Imaging: Due to its iodine content, it is utilized in molecular imaging studies, helping researchers track biological processes in vivo, which is essential for understanding disease mechanisms.
  • Antibody Labeling: Fmoc-3,5-diiodo-D-tyrosine can be employed in the labeling of antibodies for diagnostic purposes, enhancing the sensitivity and specificity of immunoassays.

Citations