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Catalog Number:
12404
CAS Number:
387824-80-8
Nα-Fmoc-Nβ-Z-D-2,3-diaminopropionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Dap(Z)-OH
Documents
$58.39 /250MG
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Product Information

Na-Fmoc-Nb-Z-D-2,3-diaminopropionic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is crucial for the selective protection of amine functionalities during the synthesis of complex peptides. Its unique structure allows for enhanced stability and solubility, making it an ideal choice for researchers focused on developing novel therapeutic agents.

In the pharmaceutical industry, Na-Fmoc-Nb-Z-D-2,3-diaminopropionic acid serves as a building block for the synthesis of bioactive peptides, which can be tailored for specific biological activities. Its application extends to the development of peptide-based drugs, where precise control over amino acid sequences is essential. Researchers appreciate its compatibility with various coupling reagents and its ability to facilitate the formation of peptide bonds, streamlining the synthesis process. This compound stands out for its efficiency in producing high-purity peptides, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-D-Dap(Z)-OH
CAS Number
387824-80-8
Purity
≥ 99% (HPLC)
Molecular Formula
C26H24N2O6
Molecular Weight
460.5
MDL Number
MFCD02684373
PubChem ID
4527114
Melting Point
157-164 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +7 ± 1º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Dap(Z)-OH
CAS Number
387824-80-8
Purity
≥ 99% (HPLC)
Molecular Formula
C26H24N2O6
Molecular Weight
460.5
MDL Number
MFCD02684373
PubChem ID
4527114
Melting Point
157-164 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +7 ± 1º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nb-Z-D-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: Its unique structure aids in the design of peptide-based drugs, enhancing their stability and bioavailability, which is crucial in pharmaceutical research.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach peptides to other biomolecules, improving targeting and efficacy in therapeutic applications.
  • Research in Neuroscience: It plays a role in developing neuropeptides that can be used to study neurological pathways, providing insights into brain function and potential treatments for neurological disorders.
  • Protein Engineering: This compound is valuable in protein engineering, where it assists in modifying proteins to enhance their function, stability, or specificity, benefiting various biotechnological applications.

Citations