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Catalog Number:
12433
CAS Number:
387824-79-5
Nα-Fmoc-Nγ-Z-D-2,4-diaminobutyric acid
Purity:
98.5 - 100.5% (Assay by titration)
Synonym(s):
Fmoc-D-Dab(Z)-OH
Documents
$71.11 /100MG
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Product Information

Na-Fmoc-Ng-Z-D-2,4-diaminobutyric acid is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability during synthesis and facilitates easy removal under mild conditions. Its unique structure allows for the incorporation of Z-protected amines, making it an excellent choice for researchers focused on developing complex peptides and biologically active molecules.

In practical applications, Na-Fmoc-Ng-Z-D-2,4-diaminobutyric acid is particularly beneficial in the pharmaceutical industry for the synthesis of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its ability to enhance solubility and stability in various solvents further supports its use in high-throughput screening and drug formulation processes. Researchers appreciate its compatibility with solid-phase peptide synthesis (SPPS), enabling efficient production of peptides with high purity and yield.

Synonyms
Fmoc-D-Dab(Z)-OH
CAS Number
387824-79-5
Purity
98.5 - 100.5% (Assay by titration)
Molecular Formula
C27H26N2O6
Molecular Weight
474.51
MDL Number
MFCD02684372
PubChem ID
73158923
Melting Point
129 - 131 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 11.5 - 13.5 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Dab(Z)-OH
CAS Number
387824-79-5
Purity
98.5 - 100.5% (Assay by titration)
Molecular Formula
C27H26N2O6
Molecular Weight
474.51
MDL Number
MFCD02684372
PubChem ID
73158923
Melting Point
129 - 131 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 11.5 - 13.5 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-Z-D-2,4-diaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. This is crucial for creating complex peptide structures in pharmaceuticals.
  • Drug Development: Its application in drug design helps in developing new therapeutic agents, particularly in targeting specific biological pathways, enhancing the efficacy and specificity of drug candidates.
  • Bioconjugation: The compound is valuable for bioconjugation processes, where it aids in attaching biomolecules to surfaces or other molecules. This is particularly useful in creating targeted drug delivery systems.
  • Research in Neuroscience: It is used in studies related to neuropeptides, contributing to the understanding of neurological functions and disorders, which can lead to new treatment options.
  • Protein Engineering: The compound plays a role in modifying proteins to enhance their stability and functionality, which is essential in various biotechnological applications, including enzyme production and therapeutic proteins.

Citations