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Catalog Number:
12646
CAS Number:
1263047-04-6
Nα-Trityl-Nβ-Fmoc-D-2,3-diaminopropionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Trt-D-Dap(Fmoc)-OH
Documents
$58.39 /100MG
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Product Information

Na-Trityl-Nb-Fmoc-D-2,3-diaminopropionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, including the trityl and Fmoc moieties, which facilitate selective reactions and enhance stability during synthesis. Its structure allows for the efficient incorporation of D-amino acids into peptides, making it an essential tool for researchers focused on developing novel therapeutics and studying protein interactions.

In addition to its applications in peptide chemistry, Na-Trityl-Nb-Fmoc-D-2,3-diaminopropionic acid is particularly valuable in the design of bioactive compounds and in the exploration of structure-activity relationships. Its ability to provide steric hindrance while maintaining solubility makes it advantageous for creating complex molecular architectures. Researchers in medicinal chemistry and biochemistry will find this compound indispensable for advancing their projects, especially in the synthesis of cyclic peptides and other advanced biomolecules.

Synonyms
Trt-D-Dap(Fmoc)-OH
CAS Number
1263047-04-6
Purity
≥ 99% (HPLC)
Molecular Formula
C37H32N2O4
Molecular Weight
568.7
MDL Number
MFCD03788168
PubChem ID
70962977
Melting Point
>102 °C (dec.)
Appearance
Off-white crystalline powder
Optical Rotation
[a]D20 = -35 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Trt-D-Dap(Fmoc)-OH
CAS Number
1263047-04-6
Purity
≥ 99% (HPLC)
Molecular Formula
C37H32N2O4
Molecular Weight
568.7
MDL Number
MFCD03788168
PubChem ID
70962977
Melting Point
>102 °C (dec.)
Appearance
Off-white crystalline powder
Optical Rotation
[a]D20 = -35 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Trityl-Nb-Fmoc-D-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its structural properties make it valuable in the design of novel pharmaceuticals, especially in the development of peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The compound can be used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: It is utilized in studies related to neuropeptides, helping researchers understand the role of specific peptides in neurological functions and disorders.
  • Protein Engineering: This chemical aids in the modification of proteins, enhancing their stability and activity, which is essential for developing more effective enzymes and therapeutic proteins.

Citations