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Catalog Number:
12763
CAS Number:
193693-60-6
Fmoc-L-β-homoproline
Purity:
≥ 95%
Synonym(s):
Fmoc-L-β-HomoPro-OH, (S-2-(1-Fmoc-2-pyrrolidinyl)acetic acid
Documents
$93.14 /250MG
Pack Size Availability Price
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Product Information

Fmoc-L-b-homoproline is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure allows for the incorporation of homoproline into peptides, enhancing their stability and bioactivity. Researchers and industry professionals appreciate Fmoc-L-b-homoproline for its ability to facilitate the formation of cyclic peptides and its role in the development of peptide-based therapeutics.

In practical applications, Fmoc-L-b-homoproline has been employed in the synthesis of bioactive peptides, which are crucial in pharmaceuticals and biotechnology. Its use can lead to improved pharmacokinetic properties and increased efficacy of peptide drugs. Additionally, this compound is beneficial in the study of protein folding and interactions, making it a valuable tool for researchers in the fields of biochemistry and molecular biology. With its robust performance and adaptability, Fmoc-L-b-homoproline stands out as a key ingredient in the advancement of peptide chemistry.

Synonyms
Fmoc-L-β-HomoPro-OH, (S-2-(1-Fmoc-2-pyrrolidinyl)acetic acid
CAS Number
193693-60-6
Purity
≥ 95%
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD01863058
PubChem ID
4384954
Appearance
White to off-white powder
Optical Rotation
[a]D = -33.0 ± 3º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-β-HomoPro-OH, (S-2-(1-Fmoc-2-pyrrolidinyl)acetic acid
CAS Number
193693-60-6
Purity
≥ 95%
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD01863058
PubChem ID
4384954
Appearance
White to off-white powder
Optical Rotation
[a]D = -33.0 ± 3º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-homoproline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of the process.
  • Drug Development: Its unique structure allows for the design of novel pharmaceuticals, particularly in developing compounds that target specific biological pathways, making it valuable in medicinal chemistry.
  • Bioconjugation: Fmoc-L-b-homoproline is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in drug delivery systems.
  • Protein Engineering: Researchers utilize this compound to modify proteins, improving their stability and functionality, which is crucial in biotechnology applications.
  • Research in Neuroscience: Its application in studying peptide interactions in the nervous system helps in understanding neurological functions and developing treatments for related disorders.

Citations