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Catalog Number:
12845
CAS Number:
352351-64-5
Fmoc-3-methyl-D-phenylalanine
Purity:
≥ 98% (Assay)
Synonym(s):
Fmoc-D-Phe(3-Me)-OH, Fmoc-m-Me-D-Phe-OH
Documents
$90.60 /1G
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Product Information

Fmoc-3-methyl-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, characterized by the presence of a 3-methylphenyl side chain, enhances its stability and solubility, making it an ideal choice for researchers focused on synthesizing complex peptides and proteins.

In practical applications, Fmoc-3-methyl-D-phenylalanine is particularly valuable in the pharmaceutical industry for the development of peptide-based therapeutics. Its ability to facilitate the synthesis of bioactive peptides allows for the exploration of new drug candidates with improved efficacy and specificity. Additionally, this compound is instrumental in the study of protein interactions and structure-function relationships, providing researchers with a powerful tool for advancing their work in biochemistry and molecular biology.

Synonyms
Fmoc-D-Phe(3-Me)-OH, Fmoc-m-Me-D-Phe-OH
CAS Number
352351-64-5
Purity
≥ 98% (Assay)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD01863049
PubChem ID
4420396
Melting Point
136 - 142 °C (Lit.)
Appearance
White solid/powder
Optical Rotation
[a]D20 = 7 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(3-Me)-OH, Fmoc-m-Me-D-Phe-OH
CAS Number
352351-64-5
Purity
≥ 98% (Assay)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD01863049
PubChem ID
4420396
Melting Point
136 - 142 °C (Lit.)
Appearance
White solid/powder
Optical Rotation
[a]D20 = 7 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-methyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: Its unique structure aids in the design of peptide-based drugs, particularly in targeting specific receptors, enhancing therapeutic efficacy.
  • Bioconjugation: The Fmoc group facilitates the attachment of peptides to various biomolecules, making it valuable in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is used to study neuropeptides, contributing to the understanding of neurological pathways and potential treatments for disorders.
  • Custom Peptide Libraries: It is instrumental in generating diverse peptide libraries for screening in drug discovery, providing a competitive edge in identifying lead compounds.

Citations